Early endosome antigen 1 (Q14911544)

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mammalian protein found in Mus musculus
  • early endosome antigen 1
  • Eea1
  • uniprot:Q8BL66
edit
Language Label Description Also known as
English
Early endosome antigen 1
mammalian protein found in Mus musculus
  • early endosome antigen 1
  • Eea1
  • uniprot:Q8BL66

Statements

molecular function
cell component
endosome
determination method or standard
IDA
IEA
6 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8BL66
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IEA
retrieved
14 February 2019
stated in
Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
early endosome
determination method or standard
IDA
IEA
ISO
ISS
25 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8BL66
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
ISS
retrieved
14 February 2019
stated in
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
ISO
retrieved
14 February 2019
stated in
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
ISO
retrieved
14 February 2019
stated in
Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
ISO
retrieved
14 February 2019
stated in
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IEA
retrieved
14 February 2019
stated in
Expression, Localization, and Biochemical Characterization of Nicotinamide Mononucleotide Adenylyltransferase 2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Intracellular lipidation of newly synthesized apolipoprotein A-I in primary murine hepatocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Normal Sorting but Defective Endocytosis of the Low Density Lipoprotein Receptor in Mice with Autosomal Recessive Hypercholesterolemia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Deficiency of sorting nexin 27 (SNX27) leads to growth retardation and elevated levels of N-methyl-D-aspartate receptor 2C (NR2C)
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Slc11a1, formerly Nramp1, is expressed in dendritic cells and influences major histocompatibility complex class II expression and antigen-presenting cell function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Goofy coordinates the acuity of olfactory signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Tetraspanin CD151 promotes cell migration by regulating integrin trafficking
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBP
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
retrieved
14 February 2019
stated in
Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BL66
determination method or standard
IDA
biological process

Identifiers

 
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