The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome (Q24293114)

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English	The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome	scientific article

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scholarly article

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7 February 2020

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome (English)

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7 February 2020

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

lysosomal associated membrane protein 1

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

SEC31 homolog A, COPII coat complex component

1 reference

GOA release 2020-03-11

SEC31 homolog B, COPII coat complex component

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Early endosome antigen 1

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Sec31 homolog B (S. cerevisiae)

1 reference

GOA release 2020-03-11

B cell CLL/lymphoma 9

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Histone deacetylase 6

1 reference

GOA release 2020-03-11

Caveolin 1, caveolae protein

1 reference

GOA release 2020-03-11

Tripartite motif-containing 50

1 reference

GOA release 2020-03-11

Sec31 homolog A (S. cerevisiae)

1 reference

GOA release 2020-03-11

Lysosomal-associated membrane protein 1

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

protein ubiquitination

1 reference

based on heuristic

inferred from title

1

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7 February 2020

4

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7 February 2020

Flora Cozzolino

7

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9

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7 February 2020

Bartolomeo Augello

6

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Bartolomeo Augello

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7 February 2020

Alessia Calcagni'

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Alessia Calcagnì

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Giuseppe Merla

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7 February 2020

author name string

Mikhail Egorov

3

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7 February 2020

Ester Valentina D'Addetta

5

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7 February 2020

Roman S Polishchuk

10

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7 February 2020

Gerard Didelot

11

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7 February 2020

Alexandre Reymond

12

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publication date

9 July 2012

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7 February 2020

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7 February 2020

7

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7

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7 February 2020

e40440

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7 February 2020

copyright license

Creative Commons Attribution 4.0 International

9 July 2012

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April 2022 Public Data File from Crossref

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based on heuristic

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BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins

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19 March 2017

Parkin mono-ubiquitinates Bcl-2 and regulates autophagy

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19 March 2017

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

1 reference

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19 March 2017

Faciogenital dysplasia protein (FGD1) regulates export of cargo proteins from the golgi complex via Cdc42 activation

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19 March 2017

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

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19 March 2017

Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase

1 reference

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19 March 2017

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

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19 March 2017

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

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19 March 2017

Charge modification at multiple C-terminal lysine residues regulates p53 oligomerization and its nucleus-cytoplasm trafficking

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19 March 2017

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

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19 March 2017

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

1 reference

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19 March 2017

The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3

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19 March 2017

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392214

19 March 2017

The tripartite motif family identifies cell compartments

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19 March 2017

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

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19 March 2017

Autophagy in the Pathogenesis of Disease

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19 March 2017

Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally

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19 March 2017

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

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19 March 2017

Identification of additional transcripts in the Williams-Beuren syndrome critical region

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19 March 2017

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

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7 April 2017

Protein degradation and protection against misfolded or damaged proteins

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7 April 2017

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

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Proteomic characterization of aggregating proteins after the inhibition of the ubiquitin proteasome system

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27 September 2017

Selective degradation of p62 by autophagy

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27 September 2017

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

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27 September 2017

Copy number variants at Williams-Beuren syndrome 7q11.23 region.

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Physiological significance of selective degradation of p62 by autophagy

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27 September 2017

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy

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27 September 2017

Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease

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27 September 2017

Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry

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27 September 2017

The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation.

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27 September 2017

HDAC6 a new cellular stress surveillance factor.

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27 September 2017

p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis

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27 September 2017

Sequestosome 1/p62--more than just a scaffold

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27 September 2017

Proteomic analysis of ubiquitinated proteins from human MCF-7 breast cancer cells by immunoaffinity purification and mass spectrometry.

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27 September 2017

TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases

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27 September 2017

Retrovirus restriction by TRIM5alpha variants from Old World and New World primates

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27 September 2017

Correlative light-electron microscopy reveals the tubular-saccular ultrastructure of carriers operating between Golgi apparatus and plasma membrane

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27 September 2017

UbiProt: a database of ubiquitylated proteins

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30 May 2018

TRIM proteins and cancer.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040440

21 January 2018

Cytoplasmic dynein/dynactin mediates the assembly of aggresomes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040440

21 January 2018

Establishment of fibroblast cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22792322

12 December 2020

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inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0040440

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2012PLoSO...740440F

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