Disabled 1 (Q14916490)

http://www.ebi.ac.uk/interpro/protein/P97318

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

PTB/PI domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

Disabled-1 interacts with a novel developmentally regulated protocadherin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

14 references

9 May 2019

Disabled-1 interacts with a novel developmentally regulated protocadherin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Inhibition of ubiquitin ligase Siah-1A by disabled-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

High affinity binding of Dab1 to Reelin receptors promotes normal positioning of upper layer cortical plate neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Inhibition of ubiquitin ligase Siah-1A by disabled-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Disabled-1 interacts with a novel developmentally regulated protocadherin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Crystal structures of the Dab homology domains of mouse disabled 1 and 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

1 reference

9 May 2019

Disabled-1 interacts with a novel developmentally regulated protocadherin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

intracellular anatomical structure

TAS

cell component

1 reference

7 November 2018

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97318&geneProductId=UniProtKB:P97318

perinuclear region of cytoplasm

TAS

1 reference

9 May 2019

Interaction of reelin signaling and Lis1 in brain development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

negative regulation of cell adhesion

1 reference

9 May 2019

Disabled-1-regulated adhesion of migrating neurons to radial glial fiber contributes to neuronal positioning during early corticogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

negative regulation of astrocyte differentiation

1 reference

9 May 2019

Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

intracellular signal transduction

1 reference

9 May 2019

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

small GTPase mediated signal transduction

TAS

1 reference

9 May 2019

Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

lateral motor column neuron migration

1 reference

14 February 2019

Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

cerebellum structural organization

1 reference

9 May 2019

Neuronal position in the developing brain is regulated by mouse disabled-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

ventral spinal cord development

1 reference

14 February 2019

Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

multicellular organism development

IEP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

1 reference

9 May 2019

Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

central nervous system development

1 reference

9 May 2019

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

positive regulation of neuron differentiation

1 reference

9 May 2019

Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

cerebral cortex development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration

1 reference

9 May 2019

Disabled-1-regulated adhesion of migrating neurons to radial glial fiber contributes to neuronal positioning during early corticogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

cerebral cortex cell migration

1 reference

9 May 2019

High affinity binding of Dab1 to Reelin receptors promotes normal positioning of upper layer cortical plate neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration

adult walking behavior

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

positive regulation of protein kinase activity

1 reference

9 May 2019

Reelin activates SRC family tyrosine kinases in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

negative regulation of receptor signaling pathway via JAK-STAT

IGI

1 reference

9 May 2019

Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Disabled-1-regulated adhesion of migrating neurons to radial glial fiber contributes to neuronal positioning during early corticogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

cerebral cortex radially oriented cell migration

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Neuronal position in the developing brain is regulated by mouse disabled-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis

hippocampus development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97318

1 reference

InterPro Release 71.0