c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK (Q24291602)

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Amyloid beta (A4) precursor protein

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Amyloid beta (A4) precursor protein-binding, family B, member 1

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Amyloid beta (A4) precursor protein-binding, family A, member 2

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Disabled 1

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S Matsuda

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Matsuda

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T Yasukawa

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Yasukawa

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Y Homma

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Homma

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Y Ito

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Ito

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T Niikura

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Niikura

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T Hiraki

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Hiraki

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S Hirai

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Hirai

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S Ohno

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Ohno

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Y Kita

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Kita

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M Kawasumi

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Kawasumi

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K Kouyama

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Kouyama

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T Yamamoto

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Yamamoto

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J M Kyriakis

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Kyriakis

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I Nishimoto

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Nishimoto

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language of work or name

English

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publication date

1 September 2001

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published in

Journal of Neuroscience

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volume

21

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issue

17

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page(s)

6597-6607

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Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.

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cites work

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12 December 2020

Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata.

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12 December 2020

The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif

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Antibody-regulated neurotoxic function of cell-surface beta-amyloid precursor protein

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Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators.

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Intrinsic signaling function of APP as a novel target of three V642 mutations linked to familial Alzheimer's disease.

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A simple and very efficient method for generating cDNA libraries

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NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell

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A phosphotyrosine interaction domain

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Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons

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12 December 2020

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

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12 December 2020

The JIP group of mitogen-activated protein kinase scaffold proteins

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12 December 2020

A mammalian scaffold complex that selectively mediates MAP kinase activation

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12 December 2020

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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12 December 2020

Signaling through scaffold, anchoring, and adaptor proteins

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12 December 2020

IB1 reduces cytokine-induced apoptosis of insulin-secreting cells

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12 December 2020

Coordinated Expression of β-Amyloid Precursor Protein and the Putative β-Secretase BACE and α-Secretase ADAM10 in Mouse and Human Brain

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A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis

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X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion

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The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity

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12 December 2020

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

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Individual isoforms of the amyloid beta precursor protein demonstrate differential adhesive potentials to constituents of the extracellular matrix

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A cytoplasmic inhibitor of the JNK signal transduction pathway

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Ligand-dependent G protein coupling function of amyloid transmembrane precursor

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Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein

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The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

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Expression of mutant amyloid precursor proteins induces apoptosis in PC12 cells.

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PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine

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Differential regulation of apoptosis-related genes in resistant and vulnerable subfields of the rat epileptic hippocampus.

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12 December 2020

Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein

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12 December 2020

The amyloid precursor protein interacts with Go heterotrimeric protein within a cell compartment specialized in signal transduction

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12 December 2020

Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor.

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12 December 2020

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

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12 December 2020

Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype

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12 December 2020

Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein

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12 December 2020

Molecular cloning of multiple splicing variants of JIP-1 preferentially expressed in brain

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12 December 2020

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

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Genomic organization, fine-mapping, and expression of the human islet-brain 1 (IB1)/c-Jun-amino-terminal kinase interacting protein-1 (JIP-1) gene

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12 December 2020

Analysis of brain injury following intrahippocampal administration of beta-amyloid in streptozotocin-treated rats

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12 December 2020

Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner

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12 December 2020

Multiple mechanisms underlie neurotoxicity by different types of Alzheimer's disease mutations of amyloid precursor protein.

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G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

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Death of PC12 cells and hippocampal neurons induced by adenoviral-mediated FAD human amyloid precursor protein gene expression.

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12 December 2020

The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes

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12 December 2020

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12 December 2020

pEF-BOS, a powerful mammalian expression vector

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12 December 2020

G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP.

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Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain

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12 December 2020

Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK

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12 December 2020

Alzheimer's beta-amyloid precursor protein is expressed on the surface of immediately ex vivo brain cells: a flow cytometric study.

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12 December 2020

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12 December 2020

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

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Signal transduction by the JNK group of MAP kinases

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Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

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Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

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12 December 2020

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

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Cell surface receptor function of amyloid precursor protein that activates Ser/Thr kinases.

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12 December 2020

Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein

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12 December 2020

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

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12 December 2020

10.1523/JNEUROSCI.21-17-06597.2001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763068&resulttype=core&format=json

release_24k6dec4h5alvbplkybregy25m

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Fatcat ID

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763068&resulttype=core&format=json

12 May 2020

1 reference