Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Q15317485)

Immunoglobulin-like fold

1 reference

Nuclear factor NF-kappa-B, p105 subunit

1 reference

Ankyrin repeat-containing domain superfamily

1 reference

Immunoglobulin E-set

1 reference

Death-like domain superfamily

1 reference

Rel homology domain (RHD), DNA-binding domain superfamily

1 reference

IPT domain, protein family

1 reference

Rel homology dimerisation domain, protein family

1 reference

Rel homology domain (RHD), DNA-binding domain, protein family

1 reference

Ankyrin repeat-containing domain, protein family

1 reference

NFkappaB IPT domain, protein family

1 reference

Death domain, protein family

1 reference

Rel homology domain, conserved site, protein family

1 reference

Ankyrin repeat, protein family

1 reference

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

3 references

14 February 2019

Calpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Ankrd2 is a modulator of NF-κB-mediated inflammatory responses during muscle differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

transcription factor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

7 references

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

IkappaBeta, a nuclear IkappaB protein, positively regulates the NF-kappaB-mediated expression of proinflammatory cytokines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

11 references

14 February 2019

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Functional association of cytokine-induced SH2 protein and protein kinase C in activated T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

RNA polymerase II transcription regulatory region sequence-specific DNA binding

3 references

5 June 2018

NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

DNA-binding transcription factor activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

double-stranded DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

heat shock protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

I-kappaB/NF-kappaB complex

cell component

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Regulation of mature T lymphocyte proliferation and differentiation by Par-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

protein-containing complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

response to muscle stretch

biological process

1 reference

14 February 2019

Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

NIK/NF-kappaB signaling

1 reference

5 June 2018

cellular response to mechanical stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

negative regulation of inflammatory response

1 reference

14 February 2019

Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

cellular response to dsRNA

IMP

1 reference

14 February 2019

TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

cellular response to cytokine stimulus

IMP

1 reference

14 February 2019

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

negative regulation of cytokine production

1 reference

14 February 2019

Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

I-kappaB kinase/NF-kappaB signaling

IMP

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

innate immune response

1 reference

5 June 2018

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

Role of TNF ligand and receptor family in the lymphoid organogenesis defined by gene targeting

lymph node development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

negative regulation of transcription, DNA-templated

TAS

1 reference

14 February 2019

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

negative regulation of transcription by RNA polymerase II

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

positive regulation of transcription, DNA-templated

3 references

positive regulation of transcription by RNA polymerase II

5 references

14 February 2019

The nuclear receptor ROR(alpha) exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

14 February 2019

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

cellular response to organic cyclic compound

1 reference

14 February 2019

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

transcription by RNA polymerase II

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25799&geneProductId=UniProtKB:P25799

response to oxidative stress

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

positive regulation of gene expression

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

response to organic cyclic compound

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

negative regulation of apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

cellular response to carbohydrate stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

cellular response to peptide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

positive regulation of pri-miRNA transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

cellular response to diterpene

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

cellular response to glucoside

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

cellular response to brain-derived neurotrophic factor stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

positive regulation of gene silencing by miRNA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25799

negative regulation of transcription by RNA polymerase II

3 references

ankyrin repeat-containing domain

1 reference

Rel homology dimerisation domain

1 reference

IPT domain

1 reference

Rel homology domain (RHD), DNA-binding domain

1 reference

Death domain

1 reference

Rel homology domain, conserved site

1 reference

ankyrin repeat

1 reference

NFkappaB IPT domain

1 reference

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016