TBX3 (Q18031866)

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

Phenocarta

retrieved

25 May 2020

ulnar-mammary syndrome

2 references

13 August 2019

Open Targets Platform

retrieved

24 August 2023

reference URL

https://platform.opentargets.org/evidence/ENSG00000135111/MONDO_0008411

based on heuristic

inferred from an Open Targets association score over 0.7

chromosome

human chromosome 12

genomic assembly

1 reference

1 reference

115108059

1 reference

114670255

1 reference

115121969

1 reference

114684175

1 reference

12q24.21

1 reference

15 May 2022

decreased expression in

2 references

Functional identity of hypothalamic melanocortin neurons depends on Tbx3

The roles and regulation of TBX3 in development and disease.

gene deletion association with

ulnar-mammary syndrome

determination method

case study

2 references

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

The roles and regulation of TBX3 in development and disease.

altered regulation leads to

2 references

A new PKCα/β/TBX3/E-cadherin pathway is involved in PLCε-regulated invasion and migration in human bladder cancer cells

The roles and regulation of TBX3 in development and disease.

HomoloGene ID

4371

1 reference

15 May 2022

PBB GE TBX3 219682 s at fs.png
732 × 530; 11 KB

0 references

increased expression in

2 references

The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes

The roles and regulation of TBX3 in development and disease.

2 references

TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases

The roles and regulation of TBX3 in development and disease.

2 references

The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes

The roles and regulation of TBX3 in development and disease.

2 references

Tbx3 overexpression in human gastric cancer is correlated with advanced tumor stage and nodal status and promotes cancer cell growth and invasion

The roles and regulation of TBX3 in development and disease.

3 references

Tbx3 represses PTEN and is over-expressed in head and neck squamous cell carcinoma

The roles and regulation of TBX3 in development and disease.

2 references

The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes

The roles and regulation of TBX3 in development and disease.

2 references

Expression of TBX3 in Hepatocellular Carcinoma and Its Clinical Implication

The roles and regulation of TBX3 in development and disease.

non-small-cell lung carcinoma

determination method

IEP

has effect

2 references

T-box 3 overexpression is associated with poor prognosis of non-small cell lung cancer

The roles and regulation of TBX3 in development and disease.

2 references

The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion

The roles and regulation of TBX3 in development and disease.

2 references

Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients

The roles and regulation of TBX3 in development and disease.

2 references

Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodal-dependent induction of stemness.

The roles and regulation of TBX3 in development and disease.

2 references

The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes

The roles and regulation of TBX3 in development and disease.

2 references

Overexpression of Tbx3 is correlated with Epithelial-Mesenchymal Transition phenotype and predicts poor prognosis of colorectal cancer

The roles and regulation of TBX3 in development and disease.

1 reference

4371

1 reference

4371

1 reference

4371

1

1 reference

20 April 2022

stromal cell of endometrium

2

1 reference

20 April 2022

seminal vesicula

3

1 reference

20 April 2022

prostate

4

1 reference

20 April 2022

right lobe of thyroid gland

5

1 reference

20 April 2022

right lung

6

1 reference

20 April 2022

left lobe of thyroid gland

7

1 reference

20 April 2022

placenta

8

1 reference

20 April 2022

jejunal mucosa

9

1 reference

20 April 2022

corpus epididymis

10

1 reference

20 April 2022

http://identifiers.org/ncbigene/6926

exact match

1 reference

http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069

Identifiers.org

reference URL

Identifiers

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

Ensembl transcript ID

1 reference

1 reference

1 reference

1 reference

0 references

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

Online Mendelian Inheritance in Man

19 August 2019

1 reference

inferred by common HGNC mappings on source and on Wikidata