T-box transcription factor 3 (Q21116324)

Transcription factor, T-box

1 reference

T-box superfamily

1 reference

Transcription factor, T-box, region of unknown function, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transcription factor, T-box, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

DNA-binding transcription repressor activity, RNA polymerase II-specific

2 references

27 March 2018

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15119&geneProductId=UniProtKB:O15119

8 April 2019

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

sequence-specific DNA binding

1 reference

8 April 2019

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

1 reference

8 April 2019

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

3 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

NAS

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

ISA

cell component

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

biological process

forelimb morphogenesis

1 reference

8 April 2019

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

cellular senescence

1 reference

8 April 2019

Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

branching involved in mammary gland duct morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

positive regulation of stem cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

atrioventricular bundle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

negative regulation of epithelial cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

female genitalia development

1 reference

8 April 2019

Novel mutation of TBX3 in a Japanese family with ulnar-mammary syndrome: implication for impaired sex development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15119&geneProductId=UniProtKB:O15119

1 reference

27 March 2018

male genitalia development

1 reference

8 April 2019

Novel mutation of TBX3 in a Japanese family with ulnar-mammary syndrome: implication for impaired sex development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

1 reference

8 April 2019

anterior/posterior axis specification, embryo

1 reference

8 April 2019

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

outflow tract morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

skeletal system development

1 reference

8 April 2019

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

ventricular septum morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

embryonic forelimb morphogenesis

1 reference

8 April 2019

Novel mutation of TBX3 in a Japanese family with ulnar-mammary syndrome: implication for impaired sex development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

cardiac muscle cell fate commitment

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

regulation of transcription by RNA polymerase II

TAS

1 reference

8 April 2019

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

TAS

heart morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

heart looping

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

negative regulation of myoblast differentiation

1 reference

8 April 2019

Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

specification of animal organ position

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

stem cell population maintenance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

luteinizing hormone secretion

1 reference

8 April 2019

Novel mutation of TBX3 in a Japanese family with ulnar-mammary syndrome: implication for impaired sex development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

follicle-stimulating hormone secretion

1 reference

8 April 2019

Novel mutation of TBX3 in a Japanese family with ulnar-mammary syndrome: implication for impaired sex development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

blood vessel development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

positive regulation of cell population proliferation

3 references

8 April 2019

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

roof of mouth development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

mammary placode formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

in utero embryonic development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

mesoderm morphogenesis

1 reference

8 April 2019

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

1 reference

8 April 2019

limb morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

sinoatrial node cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

positive regulation of cell cycle

1 reference

8 April 2019

Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

cardiac muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

limbic system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

embryonic hindlimb morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

animal organ morphogenesis

1 reference

8 April 2019

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

embryonic heart tube development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

embryonic digit morphogenesis

Novel mutation of TBX3 in a Japanese family with ulnar-mammary syndrome: implication for impaired sex development

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

negative regulation of transcription by RNA polymerase II

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

negative regulation of transcription, DNA-templated

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

8 April 2019

Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15119

Transcription factor, T-box, region of unknown function

has part(s)

1 reference

Transcription factor, T-box, conserved site

1 reference