Immune mechanisms in malaria: new insights in vaccine development (Q21032484)

Plasmodium knowlesi malaria in humans is widely distributed and potentially life threatening

20 April 2017

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Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum

20 April 2017

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The RTS,S malaria vaccine

20 April 2017

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Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria

20 April 2017

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T cell responses to the RTS,S/AS01e and RTS,S/AS02D malaria candidate vaccines administered according to different schedules to Ghanaian children

20 April 2017

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Protective immunity induced with the RTS,S/AS vaccine is associated with IL-2 and TNF-α producing effector and central memory CD4 T cells

20 April 2017

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Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

20 April 2017

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Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants

20 April 2017

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Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

20 April 2017

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Immunity to non-cerebral severe malaria is acquired after one or two infections

20 April 2017

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Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2

20 April 2017

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A review of malaria vaccine clinical projects based on the WHO rainbow table

20 April 2017

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Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria

20 April 2017

2 references

20 April 2017

Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component

21 January 2018

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IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection

20 April 2017

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Profiling immunity to HIV vaccines with systems biology

20 April 2017

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Acquired immunity to malaria

20 April 2017

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The dynamics of naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs230 & Pfs48/45 in a low endemic area in Tanzania

20 April 2017

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Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?

20 April 2017

1 reference

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

20 April 2017

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Malaria in pregnancy: small babies, big problem

20 April 2017

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Target identification and validation of novel antimalarials

21 January 2018

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Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination

21 January 2018

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First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

21 January 2018

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A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

21 January 2018

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Public health challenges and prospects for malaria control and elimination

21 January 2018

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Recent clinical experience with vaccines using MPL- and QS-21-containing adjuvant systems

21 January 2018

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The RTS,S vaccine candidate for malaria

21 January 2018

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Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

21 January 2018

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A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group

21 January 2018

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Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine.

21 January 2018

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Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine

21 January 2018

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Extended immunization intervals enhance the immunogenicity and protective efficacy of plasmid DNA vaccines.

21 January 2018

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A matter of timing: unsynchronized antigen expression and antigen presentation diminish secondary T cell responses.

21 January 2018

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Early signals during CD8 T cell priming regulate the generation of central memory cells

21 January 2018

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Increased memory conversion of naïve CD8 T cells activated during late phases of acute virus infection due to decreased cumulative antigen exposure

21 January 2018

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Memory precursor phenotype of CD8+ T cells reflects early antigenic experience rather than memory numbers in a model of localized acute influenza infection.

21 January 2018

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Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

21 January 2018

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Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children

21 January 2018

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Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial.

21 January 2018

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How is childhood development of immunity to Plasmodium falciparum enhanced by certain antimalarial interventions?

21 January 2018

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Genetic diversity and malaria vaccine design, testing and efficacy: preventing and overcoming 'vaccine resistant malaria'.

21 January 2018

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Detecting signatures of balancing selection to identify targets of anti-parasite immunity

21 January 2018

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The selection landscape of malaria parasites.

21 January 2018

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Strain theory of malaria: the first 50 years

21 January 2018

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Genetics of antigenic variation in Plasmodium falciparum

21 January 2018

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PfEMP1: an antigen that plays a key role in the pathogenicity and immune evasion of the malaria parasite Plasmodium falciparum

21 January 2018

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A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa

21 January 2018

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Submicroscopic infection in Plasmodium falciparum-endemic populations: a systematic review and meta-analysis

21 January 2018

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Regulating immunity to malaria

21 January 2018

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Regulatory T cells in malaria--friend or foe?

21 January 2018

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Natural regulatory T cells in malaria: host or parasite allies?

21 January 2018

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Delayed migration of Plasmodium sporozoites from the mosquito bite site to the blood

21 January 2018

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Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites

21 January 2018

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Innate recognition of malarial parasites by mammalian hosts

21 January 2018

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Specific inflammatory cell infiltration of hepatic schizonts in BALB/c mice immunized with attenuated Plasmodium yoelii sporozoites

21 January 2018

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Malaria circumsporozoite protein inhibits protein synthesis in mammalian cells

21 January 2018

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Release of malaria circumsporozoite protein into the host cell cytoplasm and interaction with ribosomes

21 January 2018

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Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial

21 January 2018

1 reference

Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area.

21 January 2018

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Cellular and molecular mechanisms of liver tolerance

21 January 2018

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Malaria impairs resistance to Salmonella through heme- and heme oxygenase-dependent dysfunctional granulocyte mobilization

21 January 2018

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The company malaria keeps: how co-infection with Epstein-Barr virus leads to endemic Burkitt lymphoma

21 January 2018

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A research agenda for malaria eradication: vaccines

21 January 2018

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21 January 2018

Plasmodium immunomics.

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The potential role of vaccines in the elimination of falciparum malaria and the eventual eradication of malaria.

21 January 2018

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Arrested Plasmodium liver stages as experimental anti-malaria vaccines

21 January 2018

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T cell memory in malaria.

21 January 2018

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CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes.

21 January 2018

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Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo

21 January 2018

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Protective CD8+ T lymphocytes in primates immunized with malaria sporozoites

21 January 2018

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Malaria parasite pre-erythrocytic infection: preparation meets opportunity

21 January 2018

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Genetically engineered, attenuated whole-cell vaccine approaches for malaria

21 January 2018

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Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity

21 January 2018

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Attenuated vaccines can recombine to form virulent field viruses

21 January 2018

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A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea.

21 January 2018

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A field trial to assess a blood-stage malaria vaccine

21 January 2018

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The importance of the spleen in malaria

21 January 2018

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The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

21 January 2018

1 reference

Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparum

21 January 2018

1 reference

Gamma-globulin and acquired immunity to human malaria.

21 January 2018

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The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and meta-analysis

21 January 2018

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Production by activated human T cells of interleukin 4 but not interferon-gamma is associated with elevated levels of serum antibodies to activating malaria antigens

21 January 2018

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Longevity and composition of cellular immune responses following experimental Plasmodium falciparum malaria infection in humans

21 January 2018

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Ex vivo cytokine and memory T cell responses to the 42-kDa fragment of Plasmodium falciparum merozoite surface protein-1 in vaccinated volunteers

21 January 2018

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Innate immunity to malaria

21 January 2018

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Immunity to malaria: more questions than answers

21 January 2018

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Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum

21 January 2018

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Protection against a malaria challenge by sporozoite inoculation

21 January 2018

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Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

21 January 2018

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Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites

21 January 2018

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Natural immunization against malaria: causal prophylaxis with antibiotics

21 January 2018

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The role of Plasmodium falciparum variant surface antigens in protective immunity and vaccine development.

21 January 2018

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Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family

21 January 2018

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Mosquito stage, transmission blocking vaccines for malaria

21 January 2018

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Evaluation of the standard membrane feeding assay (SMFA) for the determination of malaria transmission-reducing activity using empirical data.

21 January 2018

1 reference

Multiple functions of human T cells generated by experimental malaria challenge

21 January 2018

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CD8+ T effector memory cells protect against liver-stage malaria

21 January 2018

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Combining liver- and blood-stage malaria viral-vectored vaccines: investigating mechanisms of CD8+ T cell interference

21 January 2018

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Prime-boost immunization with adenoviral and modified vaccinia virus Ankara vectors enhances the durability and polyfunctionality of protective malaria CD8+ T-cell responses

21 January 2018

1 reference

Priming with an adenovirus 35-circumsporozoite protein (CS) vaccine followed by RTS,S/AS01B boosting significantly improves immunogenicity to Plasmodium falciparum CS compared to that with either malaria vaccine alone

21 January 2018

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Differential immunogenicity of various heterologous prime-boost vaccine regimens using DNA and viral vectors in healthy volunteers

21 January 2018

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Immunogenicity of the candidate malaria vaccines FP9 and modified vaccinia virus Ankara encoding the pre-erythrocytic antigen ME-TRAP in 1-6 year old children in a malaria endemic area

21 January 2018

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CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines

21 January 2018

1 reference

MIG (CXCL9) is a more sensitive measure than IFN-gamma of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines

21 January 2018

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Systems biology of vaccination for seasonal influenza in humans

21 January 2018

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Rationale and plans for developing a non-replicating, metabolically active, radiation-attenuatedPlasmodium falciparumsporozoite vaccine

21 January 2018

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Inhibitory and blocking monoclonal antibody epitopes on merozoite surface protein 1 of the malaria parasite Plasmodium falciparum.

21 January 2018

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The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodies

21 January 2018

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Functional conservation of the malaria vaccine antigen MSP-119across distantly related Plasmodium species.

21 January 2018

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Atypical memory B cells are greatly expanded in individuals living in a malaria-endemic area

21 January 2018

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Transcription status of vaccine candidate genes of Plasmodium falciparum during the hepatic phase of its life cycle

21 January 2018

1 reference

Safety and clinical outcome of experimental challenge of human volunteers with Plasmodium falciparum-infected mosquitoes: an update

21 January 2018

1 reference

Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs

21 January 2018

1 reference

21 January 2018

RTS,S/AS02A for malaria

1 reference

The development of the RTS,S malaria vaccine candidate: challenges and lessons

21 January 2018

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Strategies in HIV prevention: the A-B-C approach

21 January 2018

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Cell-mediated immune responses to Plasmodium falciparum antigens in adult Gambians.

21 January 2018

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12 December 2020

Rationale for the development of an engineered sporozoite malaria vaccine

1 reference

12 December 2020

Malaria vaccines: are we getting closer?

1 reference

12 December 2020

Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria.

1 reference

12 December 2020

Limited polymorphism in Plasmodium falciparum sexual-stage antigens

1 reference

12 December 2020

Induction of hepatic inflammatory response by Plasmodium berghei sporozoites protects BALB/c mice against challenge with Plasmodium yoelii sporozoites.

1 reference

12 December 2020

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

1 reference

12 December 2020

A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria.

1 reference

12 December 2020

Malaria in 1998: advances in diagnosis, drugs and vaccine development.

1 reference

12 December 2020

Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.3083

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2630673

1040026844

0 references

2630673

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference