CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics (Q21090521)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

0 references

0 references

12

Alexandra Trkola

Alexandra

Trkola

1 reference

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11 January 2020

7

Stuart G Turville

Stuart G

Turville

1 reference

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11 January 2020

2

Peter

Rusert

Peter Rusert

1 reference

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11 January 2020

Andreas Schweizer

1

Andreas

Schweizer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Livia Berlinger

3

Livia

Berlinger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Claudia R Ruprecht

4

Claudia R

Ruprecht

1 reference

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11 January 2020

Axel Mann

5

Axel

Mann

1 reference

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11 January 2020

Stéphanie Corthésy

6

Stéphanie

Corthésy

1 reference

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11 January 2020

Meropi Aravantinou

8

Meropi

Aravantinou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Marek Fischer

9

Marek

Fischer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Melissa Robbiani

10

Melissa

Robbiani

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Patrick Amstutz

11

Patrick

Amstutz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

language of work or name

English

0 references

publication date

25 July 2008

1 reference

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11 January 2020

1 reference

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11 January 2020

volume

4

1 reference

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11 January 2020

page(s)

e1000109

1 reference

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11 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

11 January 2020

copyright license

start time

25 July 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity

19 March 2017

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Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America

19 March 2017

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

19 March 2017

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Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

7 April 2017

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Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

7 April 2017

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7 April 2017

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7 January 2021

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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

1 reference

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A fusion inhibitor prevents spread of immunodeficiency viruses, but not activation of virus-specific T cells, by dendritic cells.

7 April 2017

1 reference

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Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission

12 September 2017

1 reference

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South Africa's experience of the closure of the cellulose sulphate microbicide trial

12 September 2017

1 reference

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Scientific and policy challenges to development of an AIDS vaccine

12 September 2017

1 reference

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12 September 2017

HIV entry inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenan

12 September 2017

1 reference

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In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10.

12 September 2017

1 reference

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DARPins: a true alternative to antibodies.

12 September 2017

1 reference

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The search for a topical dual action spermicide/microbicide

12 September 2017

1 reference

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Microbicide drug candidates to prevent HIV infection

12 September 2017

1 reference

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Ribosome display: selecting and evolving proteins in vitro that specifically bind to a target

12 September 2017

1 reference

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Isolation of intracellular proteinase inhibitors derived from designed ankyrin repeat proteins by genetic screening

12 September 2017

1 reference

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Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa

12 September 2017

1 reference

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Rapid selection of specific MAP kinase-binders from designed ankyrin repeat protein libraries

12 September 2017

1 reference

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Dawn of non-nucleoside inhibitor-based anti-HIV microbicides

12 September 2017

1 reference

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Real-time analysis of human immunodeficiency virus type 1 Env-mediated membrane fusion by fluorescence resonance energy transfer

12 September 2017

1 reference

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Engineering novel binding proteins from nonimmunoglobulin domains

12 September 2017

1 reference

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Exploiting common targets in human fertilization and HIV infection: development of novel contraceptive microbicides

12 September 2017

1 reference

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The nonnucleoside reverse transcriptase inhibitor UC-781 inhibits human immunodeficiency virus type 1 infection of human cervical tissue and dissemination by migratory cells

12 September 2017

1 reference

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Virus isolates during acute and chronic human immunodeficiency virus type 1 infection show distinct patterns of sensitivity to entry inhibitors

12 September 2017

1 reference

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In vitro and in vivo: the story of nonoxynol 9.

12 September 2017

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Intracellular kinase inhibitors selected from combinatorial libraries of designed ankyrin repeat proteins

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

12 September 2017

1 reference

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Microbicides: a new approach to preventing HIV and other sexually transmitted infections

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

HIV preferentially infects HIV-specific CD4+ T cells

12 September 2017

1 reference

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Development and validation of a gamma interferon ELISPOT assay for quantitation of cellular immune responses to varicella-zoster virus

12 September 2017

1 reference

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Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5

12 September 2017

1 reference

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Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

Oligomerization of CD4 is required for stable binding to class II major histocompatibility complex proteins but not for interaction with human immunodeficiency virus gp120.

12 September 2017

1 reference

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Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding

12 September 2017

1 reference

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Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding

12 September 2017

1 reference

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Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors

12 September 2017

1 reference

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Selection and characterization of Her2 binding-designed ankyrin repeat proteins

12 September 2017

1 reference

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A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.

27 September 2017

1 reference

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A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

A highly selected panel of anti-CD4 antibodies fails to induce anti-idiotypic antisera mediating human immunodeficiency virus neutralization

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

A region in domain 1 of CD4 distinct from the primary gp120 binding site is involved in HIV infection and virus-mediated fusion

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

Inhibition of HIV infection by a novel CD4 domain 2-specific monoclonal antibody. Dissecting the basis for its inhibitory effect on HIV-induced cell fusion

30 May 2018

1 reference

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A Method for Testing for Synergy with Any Number of Agents

30 May 2018

1 reference

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Carraguard Vaginal Gel Safety in HIV-Positive Women and Men in South Africa

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Single step protocol to purify recombinant proteins with low endotoxin contents.

21 January 2018

1 reference

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Quantification of infectious HIV-1 plasma viral load using a boosted in vitro infection protocol

21 January 2018

1 reference

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Humoral immunity to HIV-1: kinetics of antibody responses in chronic infection reflects capacity of immune system to improve viral set point.

21 January 2018

1 reference

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The effect of highly active antiretroviral therapy on binding and neutralizing antibody responses to human immunodeficiency virus type 1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Development of anti-CD4 MAb hu5A8 for treatment of HIV-1 infection: preclinical assessment in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

In vitro selection and characterization of DARPins and Fab fragments for the co-crystallization of membrane proteins: The Na(+)-citrate symporter CitS as an example

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Restricted antigenic variability of the epitope recognized by the neutralizing gp41 antibody 2F5

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453315

Scientists rethink approach to HIV gels

29 November 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000109

Characterization of recombinant human interleukin-2 with micromethods

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18654624

12 December 2020

inferred from PubMed ID database lookup

Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18654624

12 December 2020

inferred from PubMed ID database lookup

A humanized form of a CD4-specific monoclonal antibody exhibits decreased antigenicity and prolonged plasma half-life in rhesus monkeys while retaining its unique biological and antiviral properties

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18654624

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PPAT.1000109

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18654624%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

2 references