IQ motif containing GTPase activating protein 1 (Q21096417)

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mammalian protein found in Homo sapiens
  • RasGAP-like with IQ motifs
  • ras GTPase-activating-like protein IQGAP1
  • p195
  • IQGAP1
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Language Label Description Also known as
English
IQ motif containing GTPase activating protein 1
mammalian protein found in Homo sapiens
  • RasGAP-like with IQ motifs
  • ras GTPase-activating-like protein IQGAP1
  • p195
  • IQGAP1

Statements

molecular function
protein binding
determination method or standard
IPI
18 references
retrieved
8 April 2019
stated in
Ezrin interacts with the scaffold protein IQGAP1 and affects its cortical localization
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification and characterization of the Cdc42-binding site of IQGAP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
Association of RNase L with a Ras GTPase‐activating‐like protein IQGAP1 in mediating the apoptosis of a human cancer cell‐line
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
IQGAP1 modulates activation of B-Raf
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
retrieved
8 April 2019
stated in
Signaling Scaffold Protein IQGAP1 Interacts with Microtubule Plus-end Tracking Protein SKAP and Links Dynamic Microtubule Plus-end to Steer Cell Migration.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46940
determination method or standard
IPI
cell component
extracellular exosome
determination method or standard
IDA
5 references
retrieved
17 October 2017
stated in
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P46940&geneProductId=UniProtKB:P46940
determination method or standard
IDA
retrieved
17 October 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P46940&geneProductId=UniProtKB:P46940
determination method or standard
IDA
retrieved
17 October 2017
stated in
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P46940&geneProductId=UniProtKB:P46940
determination method or standard
IDA
retrieved
17 October 2017
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P46940&geneProductId=UniProtKB:P46940
determination method or standard
IDA
retrieved
17 October 2017
stated in
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
GOA
curator
UniProt
UniProt protein ID
P46940
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P46940&geneProductId=UniProtKB:P46940
determination method or standard
IDA
biological process

Identifiers

 
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