Peptidylprolyl isomerase B (Q21100333)

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mammalian protein found in Homo sapiens

peptidyl-prolyl cis-trans isomerase B
cyclophilin-like protein
PPIase B
PPIB
S-cyclophilin
CYP-S1
rotamase B
SCYLP
epididymis secretory protein Li 39
peptidylprolyl isomerase B (cyclophilin B)
Cyclophilin B

Language	Label	Description	Also known as
English	Peptidylprolyl isomerase B	mammalian protein found in Homo sapiens	peptidyl-prolyl cis-trans isomerase B cyclophilin-like protein PPIase B PPIB S-cyclophilin CYP-S1 rotamase B SCYLP epididymis secretory protein Li 39 peptidylprolyl isomerase B (cyclophilin B) Cyclophilin B

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23284

Cyclophilin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23284

Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

collagen binding

determination method or standard

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

unfolded protein binding

determination method or standard

1 reference

26 September 2017

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

protein-containing complex binding

determination method or standard

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

isomerase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

protein binding

determination method or standard

6 references

26 September 2017

Dymeclin, the gene underlying Dyggve-Melchior-Clausen syndrome, encodes a protein integral to extracellular matrix and golgi organization and is associated with protein secretion pathways critical in bone development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

An interaction map of endoplasmic reticulum chaperones and foldases

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

RNA polymerase binding

determination method or standard

1 reference

8 April 2019

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

determination method or standard

peptidyl-prolyl cis-trans isomerase activity

determination method or standard

5 references

26 September 2017

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

peptidyl-prolyl cis-trans isomerase activity

determination method or standard

6 references

8 April 2019

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

protein binding

determination method or standard

8 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Dymeclin, the gene underlying Dyggve-Melchior-Clausen syndrome, encodes a protein integral to extracellular matrix and golgi organization and is associated with protein secretion pathways critical in bone development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

An interaction map of endoplasmic reticulum chaperones and foldases

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

cyclosporin A binding

determination method or standard

protein-containing complex

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

endoplasmic reticulum lumen

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

determination method or standard

1 reference

26 September 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

determination method or standard

1 reference

26 September 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

smooth endoplasmic reticulum

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

endoplasmic reticulum chaperone complex

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

endoplasmic reticulum

determination method or standard

4 references

8 April 2019

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

perinuclear region of cytoplasm

determination method or standard

1 reference

8 April 2019

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

extracellular exosome

determination method or standard

5 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23284&geneProductId=UniProtKB:P23284

determination method or standard

determination method or standard

1 reference

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

determination method or standard

1 reference

8 April 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

extracellular exosome

determination method or standard

4 references

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

biological process

protein stabilization

determination method or standard

1 reference

8 April 2019

Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

regulation of post-translational protein modification

determination method or standard

1 reference

8 April 2019

Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

positive regulation by host of viral genome replication

determination method or standard

1 reference

8 April 2019

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

positive regulation by host of viral process

determination method or standard

1 reference

8 April 2019

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

protein folding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

positive regulation of multicellular organism growth

determination method or standard

1 reference

8 April 2019

Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

bone development

determination method or standard

1 reference

8 April 2019

Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

chaperone-mediated protein folding

determination method or standard

protein peptidyl-prolyl isomerization

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

8 April 2019

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

protein refolding

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23284

determination method or standard

Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23284

Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23284

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000300026

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000300026

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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