Ribosomal protein L5 (Q21101014)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P46777

Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

1 reference

8 April 2019

protein binding

12 references

8 April 2019

Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Nucleophosmin is essential for ribosomal protein L5 nuclear export

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Up-regulation of PDCD4 in senescent human diploid fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Interaction of the HIV-1 rev cofactor eukaryotic initiation factor 5A with ribosomal protein L5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

MDMX regulation of p53 response to ribosomal stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

HDM2-binding partners: interaction with translation elongation factor EF1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

RNA binding

Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

structural constituent of ribosome

Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

IBA

mRNA 3'-UTR binding

1 reference

8 April 2019

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

ubiquitin protein ligase binding

1 reference

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

mRNA 5'-UTR binding

1 reference

8 April 2019

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

ubiquitin ligase inhibitor activity

1 reference

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

RNA binding

Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

structural constituent of ribosome

Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

5S rRNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

3 references

8 April 2019

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

IBA

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

4 references

26 September 2017

26 September 2017

NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

1 reference

26 September 2017

membrane

1 reference

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

focal adhesion

1 reference

26 September 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

intracellular anatomical structure

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

1 reference

26 September 2017

nucleolus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

4 references

26 September 2017

26 September 2017

NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

cytosolic large ribosomal subunit

Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs

2 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

26 September 2017

Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

extracellular exosome

1 reference

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46777&geneProductId=UniProtKB:P46777

nucleoplasm

1 reference

8 April 2019

The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

nucleolus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

5 references

8 April 2019

8 April 2019

The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

8 April 2019

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

4 references

8 April 2019

8 April 2019

NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

1 reference

8 April 2019

focal adhesion

1 reference

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

membrane

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

cytosolic large ribosomal subunit

Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

IBA

8 April 2019

Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

protein-containing complex

1 reference

8 April 2019

Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

synapse

Ensembl genome database project

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

extracellular exosome

1 reference

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

ribonucleoprotein complex

1 reference

8 April 2019

Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

biological process

viral transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

1 reference

8 April 2019

SRP-dependent cotranslational protein targeting to membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

1 reference

8 April 2019

ribosomal large subunit biogenesis

1 reference

8 April 2019

The role of human ribosomal proteins in the maturation of rRNA and ribosome production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

translational initiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

1 reference

8 April 2019

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

1 reference

8 April 2019

protein biosynthesis

Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

8 April 2019

positive regulation of gene expression

1 reference

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

positive regulation of translation

1 reference

8 April 2019

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

protein stabilization

1 reference

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

negative regulation of ubiquitin protein ligase activity

1 reference

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

negative regulation of ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

negative regulation of protein neddylation

1 reference

8 April 2019

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

regulation of signal transduction by p53 class mediator

1 reference

8 April 2019

The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

rRNA processing

1 reference

8 April 2019

The role of human ribosomal proteins in the maturation of rRNA and ribosome production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46777

Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P46777

Commons category

Ribosomal protein L5

0 references

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016