Zinc finger CCCH-type containing, antiviral 1 (Q21101076)

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mammalian protein found in Homo sapiens

ZAP
ADP-ribosyltransferase diphtheria toxin-like 13
zinc finger CCCH-type, antiviral 1
Zinc finger antiviral protein
inactive Poly [ADP-ribose] polymerase 13
zinc finger CCCH-type antiviral protein 1
zinc finger CCCH domain-containing protein 2
ZC3HAV1
ARTD13

Language	Label	Description	Also known as
English	Zinc finger CCCH-type containing, antiviral 1	mammalian protein found in Homo sapiens	ZAP ADP-ribosyltransferase diphtheria toxin-like 13 zinc finger CCCH-type, antiviral 1 Zinc finger antiviral protein inactive Poly [ADP-ribose] polymerase 13 zinc finger CCCH-type antiviral protein 1 zinc finger CCCH domain-containing protein 2 ZC3HAV1 ARTD13

Statements

1 reference

13 November 2019

UniProt protein ID

WWE domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7Z2W4

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7Z2W4

Zinc finger, CCCH-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

WWE domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Poly(ADP-ribose) polymerase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

3 references

8 April 2019

DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

8 April 2019

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

8 April 2019

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

determination method

3 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z2W4&geneProductId=UniProtKB:Q7Z2W4

determination method

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z2W4&geneProductId=UniProtKB:Q7Z2W4

determination method

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z2W4&geneProductId=UniProtKB:Q7Z2W4

determination method

cadherin binding

determination method

1 reference

26 September 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z2W4&geneProductId=UniProtKB:Q7Z2W4

determination method

NAD+ ADP-ribosyltransferase activity

determination method

1 reference

8 April 2019

Structural basis for lack of ADP-ribosyltransferase activity in poly(ADP-ribose) polymerase-13/zinc finger antiviral protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

determination method

1 reference

8 April 2019

Structural basis for lack of ADP-ribosyltransferase activity in poly(ADP-ribose) polymerase-13/zinc finger antiviral protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

cadherin binding

determination method

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

protein ADP-ribosylase activity

determination method

1 reference

8 April 2019

Family-wide analysis of poly(ADP-ribose) polymerase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

biological process

positive regulation of interferon-alpha production

determination method

1 reference

26 September 2017

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z2W4&geneProductId=UniProtKB:Q7Z2W4

determination method

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

response to virus

determination method

1 reference

8 April 2019

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

positive regulation of mRNA catabolic process

determination method

1 reference

8 April 2019

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

negative regulation of viral genome replication

determination method

1 reference

8 April 2019

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

positive regulation of RIG-I signaling pathway

determination method

1 reference

26 September 2017

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z2W4&geneProductId=UniProtKB:Q7Z2W4

determination method

defense response to virus

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method

1 reference

26 September 2017

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z2W4&geneProductId=UniProtKB:Q7Z2W4

determination method

innate immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

positive regulation of interferon-beta production

determination method

1 reference

26 September 2017

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z2W4&geneProductId=UniProtKB:Q7Z2W4

determination method

protein poly-ADP-ribosylation

determination method

1 reference

8 April 2019

Structural basis for lack of ADP-ribosyltransferase activity in poly(ADP-ribose) polymerase-13/zinc finger antiviral protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z2W4

determination method

poly(ADP-ribose) polymerase, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7Z2W4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7Z2W4

Zinc finger, CCCH-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q7Z2W4

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000242351

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000242351

ENSP00000419855

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000419855

ENSP00000418385

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418385

ENSP00000420107

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420107

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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