RAB8A, member RAS oncogene family (Q21108073)

http://www.ebi.ac.uk/interpro/protein/P61006

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P61006

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

3 references

1 reference

8 April 2019

Identification and characterization of multiple novel Rab-myosin Va interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

20 references

8 April 2019

Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Final stages of cytokinesis and midbody ring formation are controlled by BRUCE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Pitchfork regulates primary cilia disassembly and left-right asymmetry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Functional dissection of Rab GTPases involved in primary cilium formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Coordination of Rab8 and Rab11 in primary ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Protein LidA from Legionella is a Rab GTPase supereffector

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Functional dissection of Rab GTPases involved in primary cilium formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

1 reference

8 April 2019

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

phagocytic vesicle membrane

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Functional dissection of Rab GTPases involved in primary cilium formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

extracellular exosome

1 reference

8 April 2019

1 reference

31 October 2017

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

3 references

trans-Golgi network transport vesicle

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

trans-Golgi network membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

recycling endosome membrane

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

secretory granule membrane

IDA

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

regulation of long-term neuronal synaptic plasticity

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

regulation of protein transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

vesicle docking involved in exocytosis

1 reference

31 October 2017

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

regulation of protein localization

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

cell projection organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

G2/M transition of mitotic cell cycle

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

Golgi vesicle fusion to target membrane

TAS

1 reference

31 October 2017

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

protein localization to plasma membrane

3 references

3 references

8 April 2019

A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

Functional dissection of Rab GTPases involved in primary cilium formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

8 April 2019

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

ciliary basal body-plasma membrane docking

IDA

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

neurotransmitter receptor transport to postsynaptic membrane

TAS

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death

regulation of autophagy

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

post-translational protein modification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

TAS

regulation of exocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P61006&geneProductId=UniProtKB:P61006

intracellular protein transport

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

Rab protein signal transduction

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

cellular response to insulin stimulus

IBA

3 references

neurotransmitter receptor transport, endosome to postsynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

vesicle-mediated transport in synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61006

physically interacts with

1 reference

https://thebiogrid.org/news/227

retrieved

19 April 2020

stated in

BioGRID

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

has part(s)

small GTP-binding protein domain

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P61006

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016