Phosphoinositide kinase, FYVE-type zinc finger containing (Q21108643)

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mammalian protein found in Homo sapiens

zinc finger, FYVE domain containing 29
phosphoinositide kinase, FYVE finger containing
type III PIP kinase
1-phosphatidylinositol 3-phosphate 5-kinase
epididymis luminal protein 37
PIKFYVE
phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III
FYVE finger-containing phosphoinositide kinase
PIPkin-III
phosphatidylinositol 3-phosphate 5-kinase type III

Language	Label	Description	Also known as
English	Phosphoinositide kinase, FYVE-type zinc finger containing	mammalian protein found in Homo sapiens	zinc finger, FYVE domain containing 29 phosphoinositide kinase, FYVE finger containing type III PIP kinase 1-phosphatidylinositol 3-phosphate 5-kinase epididymis luminal protein 37 PIKFYVE phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III FYVE finger-containing phosphoinositide kinase PIPkin-III phosphatidylinositol 3-phosphate 5-kinase type III

Statements

1 reference

13 November 2019

UniProt protein ID

Zinc finger, FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

Winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

Zinc finger, RING/FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

TCP-1-like chaperonin intermediate domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

Phosphatidylinositol-4-phosphate 5-kinase, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

GroEL-like apical domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

Chaperonin Cpn60/TCP-1 family

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

FYVE zinc finger, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, FYVE-related, protein family

1 reference

based on heuristic

inferred from protein domain or family

Phosphatidylinositol-4-phosphate 5-kinase, core domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DEP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PIKfyve, DEP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

zinc ion binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

protein binding

determination method

5 references

8 April 2019

The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

8 April 2019

Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

8 April 2019

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

8 April 2019

Btk-dependent regulation of phosphoinositide synthesis

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

phosphatidylinositol phosphate kinase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

determination method

2 references

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

1-phosphatidylinositol-3-phosphate 5-kinase activity

determination method

protein folding chaperone activity

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2I7&geneProductId=UniProtKB:Q9Y2I7

determination method

unfolded protein binding

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2I7&geneProductId=UniProtKB:Q9Y2I7

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

early endosome membrane

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

8 April 2019

Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

8 April 2019

The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

late endosome membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

cell-cell junction

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

vesicle membrane

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

perinuclear region of cytoplasm

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

determination method

1 reference

8 April 2019

Btk-dependent regulation of phosphoinositide synthesis

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

endosome membrane

determination method

cytoplasmic vesicle

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

biological process

phosphatidylinositol metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

phosphorylation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

myelin assembly

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

receptor-mediated endocytosis

determination method

1 reference

8 April 2019

PIKfyve Controls Fluid Phase Endocytosis but Not Recycling/Degradation of Endocytosed Receptors or Sorting of Procathepsin D by Regulating Multivesicular Body Morphogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

regulation of autophagosome assembly

determination method

1 reference

8 April 2019

PI(5)P regulates autophagosome biogenesis

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

phosphatidylinositol phosphate biosynthetic process

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

retrograde transport, endosome to Golgi

determination method

2 references

phosphatidylinositol 5-phosphate metabolic process

determination method

1 reference

8 April 2019

PI(5)P regulates autophagosome biogenesis

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

protein localization to nucleus

determination method

1 reference

8 April 2019

The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

phosphatidylinositol biosynthetic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

phosphatidylinositol-3-phosphate biosynthetic process

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2I7

determination method

'de novo' protein folding

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2I7&geneProductId=UniProtKB:Q9Y2I7

determination method

chaperone-mediated protein folding

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2I7&geneProductId=UniProtKB:Q9Y2I7

determination method

protein folding

determination method

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2I7&geneProductId=UniProtKB:Q9Y2I7

determination method

FYVE zinc finger

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

Zinc finger, FYVE-related

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

Phosphatidylinositol-4-phosphate 5-kinase, core

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

PIKfyve, DEP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2I7

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000264380

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000264380

ENSP00000308715

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000308715

ENSP00000376038

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000376038

ENSP00000384356

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000384356

ENSP00000405736

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000405736

ENSP00000407692

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000407692

ENSP00000414477

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000414477

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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