The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. (Q24301637)

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29 December 2019

title

The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport (English)

1 reference

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Phosphoinositide kinase, FYVE-type zinc finger containing

29 December 2019

main subject

cell biology

0 references

1 reference

retrograde transport, endosome to Golgi

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Jeremy G Carlton

6

1 reference

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29 December 2019

Peter J Cullen

8

1 reference

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29 December 2019

7

Harald Stenmark

1 reference

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29 December 2019

author name string

Anna C Rutherford

1

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29 December 2019

Colin Traer

2

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29 December 2019

Thomas Wassmer

3

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29 December 2019

Krupa Pattni

4

1 reference

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29 December 2019

Miriam V Bujny

5

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29 December 2019

language of work or name

English

0 references

publication date

5 September 2006

1 reference

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29 December 2019

published in

Journal of Cell Science

1 reference

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29 December 2019

volume

119

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29 December 2019

issue

Pt 19

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29 December 2019

page(s)

3944-3957

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describes a project that uses

29 December 2019

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1904490/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1

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Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport

19 March 2017

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Mutations in PIP5K3 are associated with François-Neetens mouchetée fleck corneal dystrophy

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Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides

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Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor

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Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer

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PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49

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PIKfyve Controls Fluid Phase Endocytosis but Not Recycling/Degradation of Endocytosed Receptors or Sorting of Procathepsin D by Regulating Multivesicular Body Morphogenesis

19 March 2017

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Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

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Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells

19 March 2017

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Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology

19 March 2017

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Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast

19 March 2017

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Ent5p is required with Ent3p and Vps27p for ubiquitin-dependent protein sorting into the multivesicular body.

19 March 2017

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Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors

19 March 2017

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Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S.

19 March 2017

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Vacuole Size Control: Regulation of PtdIns(3,5)P2Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P2-specific Phosphatase

19 March 2017

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Ent3p Is a PtdIns(3,5)P2 effector required for protein sorting to the multivesicular body.

19 March 2017

1 reference

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Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body

19 March 2017

1 reference

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Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p

19 March 2017

1 reference

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The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae

19 March 2017

1 reference

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Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis

19 March 2017

1 reference

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Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole

19 March 2017

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Receptor downregulation and multivesicular-body sorting

19 March 2017

1 reference

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Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion

19 March 2017

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19 March 2017

1 reference

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Active PIKfyve Associates with and Promotes the Membrane Attachment of the Late Endosome-to-trans-Golgi Network Transport Factor Rab9 Effector p40

19 March 2017

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Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization

19 March 2017

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19 March 2017

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The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradation

19 March 2017

1 reference

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Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localization

19 March 2017

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Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

19 March 2017

1 reference

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Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytes

19 March 2017

1 reference

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PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases

19 March 2017

1 reference

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19 March 2017

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Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

Rab conversion as a mechanism of progression from early to late endosomes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

The biogenesis of multivesicular endosomes

7 April 2017

1 reference

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The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology.

7 April 2017

1 reference

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The GGA proteins: adaptors on the move

27 September 2017

1 reference

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Endocytosed Cation-Independent Mannose 6-Phosphate Receptor Traffics via the Endocytic Recycling Compartment en Route to thetrans-Golgi Network and a Subpopulation of Late Endosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

PI3P signaling regulates receptor sorting but not transport in the endosomal pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells

27 September 2017

1 reference

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Mosaic organization of the endocytic pathway

27 September 2017

1 reference

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Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity

27 September 2017

1 reference

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Sorting in the endosomal system in yeast and animal cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

Mannose 6-phosphate receptors and lysosomal enzyme targeting

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

A Clinical and Histopathological Study of François-Neetens Speckled Corneal Dystrophy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1904490

The arguments for pre-existing early and late endosomes

27 September 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16954148

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Maturation models for endosome and lysosome biogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16954148

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.03153

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16954148%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16954148%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

16954148

1 reference