LIM zinc finger domain containing 1 (Q21108745)

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mammalian protein found in Homo sapiens
  • renal carcinoma antigen NY-REN-48
  • LIMS1
  • LIM and senescent cell antigen-like-containing domain protein 1
  • LIM-type zinc finger domains 1
  • LIM and senescent cell antigen-like domains 1
  • PINCH-1
  • particularly interesting new Cys-His protein 1
  • senescent cell antigen
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Language Label Description Also known as
English
LIM zinc finger domain containing 1
mammalian protein found in Homo sapiens
  • renal carcinoma antigen NY-REN-48
  • LIMS1
  • LIM and senescent cell antigen-like-containing domain protein 1
  • LIM-type zinc finger domains 1
  • LIM and senescent cell antigen-like domains 1
  • PINCH-1
  • particularly interesting new Cys-His protein 1
  • senescent cell antigen

Statements

molecular function
protein binding
determination method
IPI
14 references
retrieved
9 May 2019
stated in
The structural basis of integrin-linked kinase-PINCH interactions
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
The roles of two distinct regions of PINCH-1 in the regulation of cell attachment and spreading
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
The structural basis of integrin-linked kinase-PINCH interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
Protein interactions of the transcription factor Hoxa1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
retrieved
9 May 2019
stated in
Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IPI
cell component
focal adhesion
determination method
IDA
IEA
5 references
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48059&geneProductId=UniProtKB:P48059
determination method
IEA
retrieved
17 October 2017
stated in
The roles of two distinct regions of PINCH-1 in the regulation of cell attachment and spreading
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48059&geneProductId=UniProtKB:P48059
determination method
IDA
retrieved
17 October 2017
stated in
PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48059&geneProductId=UniProtKB:P48059
determination method
IDA
retrieved
17 October 2017
stated in
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48059&geneProductId=UniProtKB:P48059
determination method
IDA
retrieved
17 October 2017
stated in
Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48059&geneProductId=UniProtKB:P48059
determination method
IDA
focal adhesion
determination method
HDA
IBA
IDA
IEA
6 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IEA
retrieved
9 May 2019
stated in
PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IDA
retrieved
9 May 2019
stated in
The roles of two distinct regions of PINCH-1 in the regulation of cell attachment and spreading
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IDA
retrieved
9 May 2019
stated in
Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
IBA
retrieved
9 May 2019
stated in
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
GOA
curator
UniProt
UniProt protein ID
P48059
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48059
determination method
HDA
biological process

Identifiers

 
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