Caveolin 2 (Q21110568)

http://www.ebi.ac.uk/interpro/protein/P51636

Caveolin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein-macromolecule adaptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

protein homodimerization activity

1 reference

8 April 2019

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

scaffold protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

6 references

8 April 2019

MLC1 trafficking and membrane expression in astrocytes: role of caveolin-1 and phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Molecular composition and ultrastructure of the caveolar coat complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

protein heterodimerization activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

molecular adaptor activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

D1 dopamine receptor binding

1 reference

27 March 2018

D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

IPI

protein kinase binding

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

structural molecule activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

molecular adaptor activity

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

2 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

extrinsic component of cytoplasmic side of plasma membrane

1 reference

8 April 2019

D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

integral component of plasma membrane

1 reference

27 March 2018

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

intracellular anatomical structure

1 reference

27 March 2018

Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

perinuclear region of cytoplasm

1 reference

27 March 2018

Serine 23 and 36 phosphorylation of caveolin-2 is differentially regulated by targeting to lipid raft/caveolae and in mitotic endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

9 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

Molecular composition and ultrastructure of the caveolar coat complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

Serine 23 and 36 phosphorylation of caveolin-2 is differentially regulated by targeting to lipid raft/caveolae and in mitotic endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

1 reference

8 April 2019

BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

1 reference

27 March 2018

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

3 references

10 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Molecular composition and ultrastructure of the caveolar coat complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Serine 23 and 36 phosphorylation of caveolin-2 is differentially regulated by targeting to lipid raft/caveolae and in mitotic endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

protein-containing complex

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Molecular composition and ultrastructure of the caveolar coat complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

insulin receptor signaling pathway

biological process

1 reference

27 March 2018

A novel domain of caveolin-2 that controls nuclear targeting: regulation of insulin-specific ERK activation and nuclear translocation by caveolin-2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

positive regulation of endothelial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

3 references

27 March 2018

Involvement of caveolin-2 in caveolar biogenesis in MDCK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

27 March 2018

The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

1 reference

8 April 2019

The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

negative regulation of transforming growth factor beta receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

positive regulation of dopamine receptor signaling pathway

1 reference

8 April 2019

D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

1 reference

8 April 2019

The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

positive regulation of GTPase activity

1 reference

8 April 2019

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

positive regulation by host of viral process

1 reference

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

protein complex oligomerization

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

receptor-mediated endocytosis of virus by host cell

1 reference

8 April 2019

The Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirus

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

1 reference

8 April 2019

The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

positive regulation of MAPK cascade

1 reference

27 March 2018

A novel domain of caveolin-2 that controls nuclear targeting: regulation of insulin-specific ERK activation and nuclear translocation by caveolin-2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51636&geneProductId=UniProtKB:P51636

regulation of mitotic nuclear division

1 reference

8 April 2019

Serine 23 and 36 phosphorylation of caveolin-2 is differentially regulated by targeting to lipid raft/caveolae and in mitotic endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

negative regulation of cell population proliferation

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

negative regulation of endothelial cell proliferation

3 references

insulin receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

positive regulation of MAPK cascade

4 references

8 April 2019

Involvement of caveolin-2 in caveolar biogenesis in MDCK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51636

has part(s)

Caveolin, conserved site

1 reference

stated in

InterPro Release 71.0