NEDD4 like E3 ubiquitin protein ligase (Q21112132)

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mammalian protein found in Homo sapiens
  • ubiquitin-protein ligase Rsp5
  • NEDD4.2
  • HECT-type E3 ubiquitin transferase NED4L
  • Nedd4-2
  • E3 ubiquitin-protein ligase NEDD4-like
  • NEDD4L
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
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Language Label Description Also known as
English
NEDD4 like E3 ubiquitin protein ligase
mammalian protein found in Homo sapiens
  • ubiquitin-protein ligase Rsp5
  • NEDD4.2
  • HECT-type E3 ubiquitin transferase NED4L
  • Nedd4-2
  • E3 ubiquitin-protein ligase NEDD4-like
  • NEDD4L
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

Statements

molecular function
protein binding
determination method
IPI
10 references
retrieved
8 April 2019
stated in
Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
Identification of NPC2 protein as interaction molecule with C2 domain of human Nedd4L
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
retrieved
8 April 2019
stated in
Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IPI
cell component
biological process
protein ubiquitination
determination method
IBA
IDA
IEA
IMP
NAS
6 references
retrieved
8 April 2019
stated in
The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
NAS
retrieved
8 April 2019
stated in
Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IEA
retrieved
8 April 2019
stated in
Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response
GOA
curator
UniProt
UniProt protein ID
Q96PU5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IDA
retrieved
8 April 2019
stated in
Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PU5
determination method
IBA

Identifiers

RefSeq protein ID
Ensembl protein ID
 
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