Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2 (Q24295274)

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English	Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2	scientific article

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10 February 2020

Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2 (English)

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10 February 2020

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GOA release 2020-03-11

NEDD4 like E3 ubiquitin protein ligase

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GOA release 2020-03-11

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10 February 2020

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Jun Guo

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10 February 2020

Xian Li

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10 February 2020

Heidi Shallow

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10 February 2020

Tonghua Yang

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10 February 2020

Wentao Li

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10 February 2020

Jianmin Xu

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10 February 2020

Michael D Fridman

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10 February 2020

Xiaolong Yang

9

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10 February 2020

Shetuan Zhang

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9 August 2012

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10 February 2020

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10

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Journal of Biological Chemistry

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33132-33141

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10 February 2020

Nedd4-2-dependent ubiquitylation and regulation of the cardiac potassium channel hERG1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

19 March 2017

Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

19 March 2017

ESCRT complexes and the biogenesis of multivesicular bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

19 March 2017

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

19 March 2017

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

19 March 2017

The caveolin proteins

1 reference

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19 March 2017

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

1 reference

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19 March 2017

HERG, a human inward rectifier in the voltage-gated potassium channel family

1 reference

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19 March 2017

Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

1 reference

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19 March 2017

Physiological functions of the HECT family of ubiquitin ligases

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7 April 2017

C2-domains, structure and function of a universal Ca2+-binding domain

1 reference

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7 April 2017

Interaction between the cardiac rapidly (IKr) and slowly (IKs) activating delayed rectifier potassium channels revealed by low K+-induced hERG endocytic degradation.

1 reference

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27 September 2017

Involvement of caveolin in probucol-induced reduction in hERG plasma-membrane expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

27 September 2017

Short QT syndrome: from bench to bedside.

1 reference

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27 September 2017

Involvement of caveolin in low K+-induced endocytic degradation of cell-surface human ether-a-go-go-related gene (hERG) channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

27 September 2017

Extracellular K+ is a prerequisite for the function and plasma membrane stability of HERG channels

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

27 September 2017

Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines

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27 September 2017

Endocytic regulation of TGF-beta signaling

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27 September 2017

The C1 and C2 domains target human type 6 adenylyl cyclase to lipid rafts and caveolae.

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27 September 2017

Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol

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27 September 2017

Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes

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27 September 2017

Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

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27 September 2017

Internalization of large double-membrane intercellular vesicles by a clathrin-dependent endocytic process

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27 September 2017

hERG potassium channels and cardiac arrhythmia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

27 September 2017

Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460420

27 September 2017

The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin

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27 September 2017

Clathrin-independent endocytosis of ubiquitinated cargos

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27 September 2017

Fibronectin matrix turnover occurs through a caveolin-1-dependent process

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27 September 2017

Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins

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27 September 2017

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

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27 September 2017

Sudden death associated with short-QT syndrome linked to mutations in HERG.

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27 September 2017

Caveolae/raft-dependent endocytosis

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27 September 2017

Caveolae: from cell biology to animal physiology

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27 September 2017

Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation

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27 September 2017

Molecular and cellular mechanisms of cardiac arrhythmias

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27 September 2017

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27 September 2017

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27 September 2017

Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles

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27 September 2017

The role of monoubiquitination in endocytic degradation of human ether-a-go-go-related gene (hERG) channels under low K+ conditions

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30 May 2018

Circulating integrins: alpha 5 beta 1, alpha 6 beta 4 and Mac-1, but not alpha 3 beta 1, alpha 4 beta 1 or LFA-1

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30 May 2018

Low birth weight and increased sympathetic activity

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Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4.

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21 January 2018

Mechanisms of arsenic-induced prolongation of cardiac repolarization

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10.1074/JBC.M112.389643

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10 February 2020

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10 February 2020

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10 February 2020

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