TGF-beta activated kinase 1 (MAP3K7) binding protein 2 (Q21112848)

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mammalian protein found in Homo sapiens
  • TAB-2
  • TAB2
  • TGF-beta-activated kinase 1-binding protein 2
  • TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
  • mitogen-activated protein kinase kinase kinase 7-interacting protein 2
  • TAK1-binding protein 2
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Language Label Description Also known as
English
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
mammalian protein found in Homo sapiens
  • TAB-2
  • TAB2
  • TGF-beta-activated kinase 1-binding protein 2
  • TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
  • mitogen-activated protein kinase kinase kinase 7-interacting protein 2
  • TAK1-binding protein 2

Statements

molecular function
protein binding
determination method
IPI
16 references
retrieved
8 April 2019
stated in
RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation
GOA
curator
UniProt
UniProt protein ID
Q9NYJ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
GOA
curator
UniProt
UniProt protein ID
Q9NYJ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
Mutations in MAP3K7 that Alter the Activity of the TAK1 Signaling Complex Cause Frontometaphyseal Dysplasia
GOA
curator
UniProt
UniProt protein ID
Q9NYJ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
GOA
curator
UniProt
UniProt protein ID
Q9NYJ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
HSP90 is required for TAK1 stability but not for its activation in the pro-inflammatory signaling pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
Direct activation of protein kinases by unanchored polyubiquitin chains
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
The Yersinia enterocolitica effector YopP inhibits host cell signalling by inactivating the protein kinase TAK1 in the IL-1 signalling pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
Inhibition of autophagy by TAB2 and TAB3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
TAK1-dependent signaling requires functional interaction with TAB2/TAB3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
retrieved
8 April 2019
stated in
Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYJ8
determination method
IPI
cell component
biological process

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21112848&oldid=2022951170"