Microtubule associated protein 1 light chain 3 beta (Q21115138)

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mammalian protein found in Homo sapiens
  • autophagy-related ubiquitin-like modifier LC3 B
  • Autophagy-related protein LC3 B
  • MAP1 light chain 3-like protein 2
  • MAP1LC3B
  • MAP1A/MAP1B light chain 3 B
  • MAP1A/MAP1B LC3 B
  • Microtubule-associated protein 1 light chain 3 beta
  • microtubule-associated proteins 1A/1B light chain 3B
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Language Label Description Also known as
English
Microtubule associated protein 1 light chain 3 beta
mammalian protein found in Homo sapiens
  • autophagy-related ubiquitin-like modifier LC3 B
  • Autophagy-related protein LC3 B
  • MAP1 light chain 3-like protein 2
  • MAP1LC3B
  • MAP1A/MAP1B light chain 3 B
  • MAP1A/MAP1B LC3 B
  • Microtubule-associated protein 1 light chain 3 beta
  • microtubule-associated proteins 1A/1B light chain 3B

Statements

molecular function
protein binding
determination method
IPI
37 references
retrieved
9 May 2019
stated in
Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
GOA
curator
UniProt
UniProt protein ID
Q9GZQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Nix, a receptor protein for mitophagy in mammals
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Network organization of the human autophagy system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Regulation of endoplasmic reticulum turnover by selective autophagy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
A human protein-protein interaction network: a resource for annotating the proteome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Nix is a selective autophagy receptor for mitochondrial clearance
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
A directed protein interaction network for investigating intracellular signal transduction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Phosphorylation of NBR1 by GSK3 modulates protein aggregation.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Autophagy mediates degradation of nuclear lamina
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
retrieved
9 May 2019
stated in
Regulation of endoplasmic reticulum turnover by selective autophagy
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9GZQ8
determination method
IPI
cell component
biological process

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21115138&oldid=2022961115"