Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta (Q21115992)

Ubiquitin-like domain superfamily

1 reference

Protein kinase-like domain superfamily

1 reference

C2 domain superfamily

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily

1 reference

Phosphatidylinositol kinase family

1 reference

Armadillo-type fold

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family

1 reference

Phosphatidylinositol 3-kinase, C2 domain, protein family

1 reference

Phosphatidylinositol 3-kinase adaptor-binding (PI3K ABD) domain, protein family

1 reference

Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain, protein family

1 reference

Phosphoinositide 3-kinase, accessory (PIK) domain, protein family

1 reference

PI3Kbeta, catalytic domain, protein family

1 reference

Phosphatidylinositol 3/4-kinase, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1-phosphatidylinositol-4-phosphate 3-kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 references

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Charting the molecular network of the drug target Bcr-Abl

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Pooled-matrix protein interaction screens using Barcode Fusion Genetics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

insulin receptor substrate binding

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1-phosphatidylinositol-3-kinase activity

IDA

4 references

8 April 2019

The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol-3,4-bisphosphate 5-kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol 3-kinase complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

positive regulation of autophagy

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

Fc-gamma receptor signaling pathway involved in phagocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

8 April 2019

Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

angiogenesis involved in wound healing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

cellular calcium ion homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

3 references

5 June 2018

Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

Fc-epsilon receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol-3-phosphate biosynthetic process

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

phosphatidylinositol phosphate biosynthetic process

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

positive regulation of gene expression

1 reference

8 April 2019

Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

vascular endothelial growth factor receptor signaling pathway

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

endothelial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

regulation of clathrin-dependent endocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

T cell receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

homophilic cell adhesion via plasma membrane adhesion molecules

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

adaptive immune response

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

inflammatory response

1 reference

5 June 2018

positive regulation of neutrophil apoptotic process

1 reference

8 April 2019

Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

IMP

innate immune response

1 reference

5 June 2018

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

positive regulation of protein kinase B signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol 3-kinase signaling

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

5 June 2018

Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P42338&geneProductId=UniProtKB:P42338

cytokine-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol 3-kinase signaling

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

3 references

8 April 2019

Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

4 references

8 April 2019

Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol-3-phosphate biosynthetic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol-mediated signaling

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

phosphatidylinositol biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42338

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6741

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6004

language of work or name

English

retrieved

17 August 2016

has part(s)

Phosphatidylinositol 3-kinase adaptor-binding (PI3K ABD) domain

1 reference

Phosphoinositide 3-kinase, accessory (PIK) domain

1 reference

Phosphatidylinositol 3/4-kinase, conserved site

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain

1 reference

Phosphatidylinositol 3-kinase, C2 domain

1 reference

Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain

1 reference

PI3Kbeta, catalytic domain

1 reference