Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy (Q24302295)

positive regulation of gene expression

1 reference

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

1 reference

Thymoma viral proto-oncogene 1

1 reference

0 references

7

Bart Vanhaesebroeck

0 references

author name string

George Haddad

1

0 references

Pavel Zhabyeyev

2

0 references

Maikel Farhan

3

0 references

Lin Fu Zhu

4

0 references

Zamaneh Kassiri

5

0 references

David C Rayner

6

0 references

Gavin Y Oudit

8

0 references

Allan G Murray

Postdiarrheal Shiga toxin-mediated hemolytic uremic syndrome

9

0 references

language of work or name

English

0 references

publication date

25 September 2014

0 references

published in

Blood

0 references

volume

124

0 references

issue

13

0 references

page(s)

2142-9

0 references

cites work

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Hemolytic uremic syndrome (HUS)--incidence and etiologies at a regional Children's Hospital in 2001-2006.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Autocrine VEGF signaling is required for vascular homeostasis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

An optimized three-dimensional in vitro model for the analysis of angiogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Molecular mechanisms and clinical applications of angiogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

PI 3-kinase p110beta: a new target for antithrombotic therapy

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

The emerging mechanisms of isoform-specific PI3K signalling

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

The life of a cell: apoptosis regulation by the PI3K/PKB pathway

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

VEGF inhibition and renal thrombotic microangiopathy

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Atypical hemolytic-uremic syndrome

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

An outbreak of Shiga toxin-producing Escherichia coli O104:H4 hemolytic uremic syndrome in Germany: presentation and short-term outcome in children

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Shiga toxin-associated hemolytic uremic syndrome: advances in pathogenesis and therapeutics

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Egr-1-induced endothelial gene expression: a common theme in vascular injury

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

PI3Kβ plays a critical role in neutrophil activation by immune complexes.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Retardation of retinal vascular development in apelin-deficient mice

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Facio-genital dysplasia-5 regulates matrix adhesion and survival of human endothelial cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Rapid vascular regrowth in tumors after reversal of VEGF inhibition

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Angiopoietin-1 is essential in mouse vasculature during development and in response to injury

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Deficiency in the p110alpha subunit of PI3K results in diminished Tie2 expression and Tie2(-/-)-like vascular defects in mice

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Continuous signaling via PI3K isoforms beta and gamma is required for platelet ADP receptor function in dynamic thrombus stabilization

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

In vivo vasculogenic potential of human blood-derived endothelial progenitor cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Deletion of the p110 isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Identification and functional analysis of endothelial tip cell-enriched genes

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Small vessels, big trouble in the kidneys and beyond: hematopoietic stem cell transplantation-associated thrombotic microangiopathy

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

Experimental glomerular endothelial injury in vivo

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021

PDGF-C mediates glomerular capillary repair

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2014-02-557975

7 January 2021