Serine/threonine kinase 24 (Q21117407)

http://www.ebi.ac.uk/interpro/protein/Q9Y6E0

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

9 references

8 April 2019

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

STRIPAK components determine mode of cancer cell migration and metastasis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Structural mechanism of CCM3 heterodimerization with GCKIII kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

2 references

protein serine/threonine kinase activity

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

17 October 2017

Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

17 October 2017

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

1 reference

17 October 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

MAP kinase kinase kinase kinase activity

IDA

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

protein serine/threonine kinase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

Large-scale proteomics and phosphoproteomics of urinary exosomes

IDA

extracellular exosome

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

4 references

17 October 2017

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

17 October 2017

Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

17 October 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

5 references

8 April 2019

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

intrinsic apoptotic signaling pathway in response to oxidative stress

biological process

1 reference

8 April 2019

Mammalian sterile 20-like kinase 3 (MST3) mediates oxidative-stress-induced cell death by modulating JNK activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

regulation of axon regeneration

IMP

1 reference

8 April 2019

Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

negative regulation of cell migration

IEA

response to hydrogen peroxide

IMP

1 reference

8 April 2019

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

cellular response to starvation

IEA

1 reference

8 April 2019

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

protein autophosphorylation

IMP

3 references

8 April 2019

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

8 April 2019

CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

17 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

regulation of mitotic cell cycle

IEA

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

stress-activated protein kinase signaling cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

regulation of apoptotic process

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6E0&geneProductId=UniProtKB:Q9Y6E0

neuron projection morphogenesis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

activation of protein kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E0

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5710

protein kinase, ATP binding site

English

retrieved

17 August 2016

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y6E0

protein kinase domain

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y6E0

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016

1 reference

1 August 2016