Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST (Q24307422)

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English	Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST	scientific article

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20 December 2019

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST (English)

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20 December 2019

Serine/threonine kinase 24

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GOA release 2020-03-11

protein autophosphorylation

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GOA release 2020-03-11

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based on heuristic

inferred from title

11

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Te-Jung Lu

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Wen-Yang Lai

2

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Chi-Ying F Huang

3

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Wan-Jung Hsieh

4

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Jau-Song Yu

5

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Ya-Ju Hsieh

6

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Wen-Tsan Chang

7

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Tzeng-Horng Leu

8

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Wen-Chang Chang

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Woei-Jer Chuang

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Tzong-Yueh Chen

12

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Te-Ling Lu

13

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Ming-Derg Lai

14

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17 October 2006

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13

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Journal of Biological Chemistry

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38405-38417

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20 December 2019

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p21-activated kinases: three more join the Pak.

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PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

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Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase (auto-kinase). Evidence that auto-kinase belongs to a member of the p21-activated kinase family

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Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

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Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation

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Regulation of mammalian STE20-like kinase 2 (MST2) by protein phosphorylation/dephosphorylation and proteolysis

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Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1.

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The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1

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YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta

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YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways

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Cloning and characterization of MST4, a novel Ste20-like kinase

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MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway

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Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements

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Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis

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Identification and characterization of the nuclear import and export signals of the mammalian Ste20-like protein kinase 3.

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Zinc ion acts as a cofactor for serine/threonine kinase MST3 and has a distinct role in autophosphorylation of MST3.

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21 January 2018

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Cell migration: integrating signals from front to back

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Structural basis of collagen recognition by integrin alpha2beta1

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Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration

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21 January 2018

Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again

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An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells

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21 January 2018

Paxillin and focal adhesion signalling

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Paxillin is essential for PTP-PEST-dependent regulation of cell spreading and motility: a role for paxillin kinase linker.

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21 January 2018

Tyrosine phosphorylation of paxillin alpha is involved in temporospatial regulation of paxillin-containing focal adhesion formation and F-actin organization in motile cells

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21 January 2018

Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

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21 January 2018

Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells

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21 January 2018

Tyrosine phosphorylation of the CrkII adaptor protein modulates cell migration

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The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling

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Identifiers

10.1074/JBC.M605035200

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20 December 2019

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