MTOR associated protein, LST8 homolog (Q21117879)

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mammalian protein found in Homo sapiens

mammalian lethal with SEC13 protein 8
G protein beta subunit-like
TORC subunit LST8
protein GbetaL
gable
MLST8
target of rapamycin complex subunit LST8

Language	Label	Description	Also known as
English	MTOR associated protein, LST8 homolog	mammalian protein found in Homo sapiens	mammalian lethal with SEC13 protein 8 G protein beta subunit-like TORC subunit LST8 protein GbetaL gable MLST8 target of rapamycin complex subunit LST8

Statements

1 reference

13 November 2019

UniProt protein ID

WD40/YVTN repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVC4

Quinoprotein alcohol dehydrogenase-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVC4

Target of rapamycin complex subunit LST8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVC4

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

G-protein beta WD-40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

6 references

1 January 2018

PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

Network organization of the human autophagy system

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

Identification of Protor as a novel Rictor-binding component of mTOR complex-2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

protein serine/threonine kinase activator activity

determination method

1 reference

1 January 2018

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

determination method

2 references

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

determination method

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

16 July 2018

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

16 July 2018

PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

determination method

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

determination method

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

biological process

positive regulation of actin filament polymerization

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

regulation of actin cytoskeleton organization

determination method

1 reference

16 July 2018

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

regulation of GTPase activity

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

positive regulation of peptidyl-tyrosine phosphorylation

determination method

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

regulation of cellular response to heat

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

TORC1 signaling

determination method

1 reference

1 January 2018

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

positive regulation of protein serine/threonine kinase activity

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

regulation of macroautophagy

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

activation of protein kinase B activity

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVC4

determination method

determination method

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVC4&geneProductId=UniProtKB:Q9BVC4

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVC4

G-protein beta WD-40 repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVC4

WD40 repeat, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVC4

Identifiers

MeSH descriptor ID

subject named as

mTOR Associated Protein, LST8 Homolog

0 references

D05.500.337.250

0 references

D08.811.913.696.620.682.700.931.500.250

0 references

D12.644.360.024.310

0 references

D12.776.157.057.073

0 references

D12.776.476.024.389

0 references

D12.776.476.563.931.500.250

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000371888

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000371888

ENSP00000380313

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000380313

ENSP00000455046

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455046

ENSP00000456405

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456405

ENSP00000457870

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000457870

ENSP00000301724

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000301724

ENSP00000454235

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454235

ENSP00000454629

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454629

ENSP00000454698

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454698

ENSP00000455458

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455458

ENSP00000455475

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455475

ENSP00000455642

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455642

ENSP00000455850

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455850

ENSP00000456046

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456046

ENSP00000456063

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456063

ENSP00000456076

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456076

ENSP00000456944

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456944

ENSP00000459612

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000459612

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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