SEC31 homolog A, COPII coat complex component (Q21119692)

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mammalian protein found in Homo sapiens

SEC31-related protein A
SEC31 homolog A, COPII coating complex component
ABP130
ABP125
protein transport protein Sec31A
SEC31-like protein 1
SEC31A
web1-like protein
yeast Sec31p homolog

Language	Label	Description	Also known as
English	SEC31 homolog A, COPII coat complex component	mammalian protein found in Homo sapiens	SEC31-related protein A SEC31 homolog A, COPII coating complex component ABP130 ABP125 protein transport protein Sec31A SEC31-like protein 1 SEC31A web1-like protein yeast Sec31p homolog

Statements

1 reference

13 November 2019

UniProt protein ID

Protein transport protein SEC31-like

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method or standard

10 references

8 April 2019

The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

ALG-2 oscillates in subcellular localization, unitemporally with calcium oscillations

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

calcium-dependent protein binding

determination method or standard

structural molecule activity

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

COPII-coated ER to Golgi transport vesicle

determination method or standard

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Ubiquitin-dependent regulation of COPII coat size and function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

cytoplasmic vesicle

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

intracellular membrane-bounded organelle

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

perinuclear region of cytoplasm

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

determination method or standard

1 reference

8 April 2019

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

COPII vesicle coat

determination method or standard

3 references

16 July 2018

Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94979&geneProductId=UniProtKB:O94979

determination method or standard

16 July 2018

The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94979&geneProductId=UniProtKB:O94979

determination method or standard

16 July 2018

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94979&geneProductId=UniProtKB:O94979

determination method or standard

COPII vesicle coat

determination method or standard

4 references

8 April 2019

Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

endoplasmic reticulum exit site

determination method or standard

3 references

10 September 2018

The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94979&geneProductId=UniProtKB:O94979

determination method or standard

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94979&geneProductId=UniProtKB:O94979

determination method or standard

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94979&geneProductId=UniProtKB:O94979

determination method or standard

determination method or standard

endoplasmic reticulum exit site

determination method or standard

5 references

8 April 2019

The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

TANGO1 recruits Sec16 to coordinately organize ER exit sites for efficient secretion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

biological process

IRE1-mediated unfolded protein response

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

response to calcium ion

determination method or standard

1 reference

8 April 2019

ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

COPII vesicle coating

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

vesicle-mediated transport

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

antigen processing and presentation of exogenous peptide antigen via MHC class II

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

protein transport

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

antigen processing and presentation of peptide antigen via MHC class I

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method or standard

1 reference

16 July 2018

Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94979&geneProductId=UniProtKB:O94979

determination method or standard

COPII-coated vesicle cargo loading

determination method or standard

intracellular protein transport

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method or standard

COPII-coated vesicle cargo loading

determination method or standard

3 references

8 April 2019

Structural basis of cargo membrane protein discrimination by the human COPII coat machinery

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

COPII-coated vesicle budding

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method or standard

3 references

8 April 2019

Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

endoplasmic reticulum organization

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94979

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000309070

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000309070

ENSP00000337602

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000337602

ENSP00000347329

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000347329

ENSP00000378721

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000378721

ENSP00000400926

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400926

ENSP00000408027

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000408027

ENSP00000421464

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000421464

ENSP00000424451

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000424451

ENSP00000424635

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000424635

ENSP00000426569

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000426569

ENSP00000426886

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000426886

ENSP00000264405

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000264405

ENSP00000421001

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000421001

ENSP00000421633

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000421633

ENSP00000422267

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000422267

ENSP00000422371

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000422371

ENSP00000422563

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000422563

ENSP00000422797

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000422797

ENSP00000424336

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000424336

ENSP00000425056

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425056

ENSP00000425064

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425064

ENSP00000425095

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425095

ENSP00000425140

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425140

ENSP00000425555

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425555

ENSP00000425999

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425999

ENSP00000426562

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000426562

ENSP00000426943

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000426943

ENSP00000426950

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000426950

ENSP00000475765

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475765

ENSP00000476156

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000476156

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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