Mixed lineage kinase domain like pseudokinase (Q21120032)

Adaptor protein Cbl, N-terminal domain superfamily

1 reference

Mixed Lineage Kinase Domain-like

1 reference

Transporter Classification Database ID

1.A.105.1.1

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

3 references

8 April 2019

PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

Ensembl genome database project

IDA

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

identical protein binding

1 reference

21 June 2018

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NB16&geneProductId=UniProtKB:Q8NB16

protein-containing complex binding

IPI

1 reference

8 April 2019

The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

IDA

protein kinase activity

1 reference

8 April 2019

protein serine/threonine kinase activity

ISS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

JUN kinase kinase kinase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

protein homotrimerization

1 reference

8 April 2019

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

IDA

programmed cell death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NB16&geneProductId=UniProtKB:Q8NB16

protein phosphorylation

1 reference

27 February 2018

intracellular signal transduction

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NB16&geneProductId=UniProtKB:Q8NB16

cell surface receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NB16

protein phosphorylation

1 reference

8 April 2019

serine-threonine/tyrosine-protein kinase, catalytic domain

has part(s)

1 reference

protein kinase domain

1 reference

Transporter Classification Database ID

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

5 August 2016

language of work or name

1 reference

5 August 2016

language of work or name

1 reference

5 August 2016

language of work or name

English

1.A.105.1.1

2 references

Transporter Classification database

retrieved

13 March 2020