Paired box 2 (Q21120414)

Winged helix-like DNA-binding domain superfamily

1 reference

Paired-box protein 2 C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Paired domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

5 references

8 April 2019

Further delineation of renal-coloboma syndrome in patients with extreme variability of phenotype and identical PAX2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

superoxide-generating NAD(P)H oxidase activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02962&geneProductId=UniProtKB:Q02962

transcription factor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

cis-regulatory region sequence-specific DNA binding

IPI

1 reference

8 April 2019

PAX2 oncogene negatively regulates the expression of the host defense peptide human beta defensin-1 in prostate cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

3 references

8 April 2019

Prolyl hydroxylase domain protein 3 targets Pax2 for destruction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

Interaction of the LMX1B and PAX2 gene products suggests possible molecular basis of differential phenotypes in Nail-Patella syndrome.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

DNA-binding transcription factor activity, RNA polymerase II-specific

IPI

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

DNA-binding transcription factor activity

ISA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

Novel interaction partners of Bardet-Biedl syndrome proteins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

microtubule organizing center

1 reference

8 April 2019

Novel interaction partners of Bardet-Biedl syndrome proteins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

WNT5A is regulated by PAX2 and may be involved in blastemal predominant Wilms tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

cellular response to hydrogen peroxide

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

cellular response to glucose stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

pronephros development

1 reference

8 April 2019

cellular response to retinoic acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

regulation of metanephric nephron tubule epithelial cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

animal organ development

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02962&geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

positive regulation of branching involved in ureteric bud morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

positive regulation of metanephric DCT cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

regulation of metanephros size

1 reference

8 April 2019

A common variant of the PAX2 gene is associated with reduced newborn kidney size

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

Further delineation of renal-coloboma syndrome in patients with extreme variability of phenotype and identical PAX2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

protein kinase B signaling

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

negative regulation of apoptotic process involved in metanephric collecting duct development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

positive regulation of epithelial cell proliferation

1 reference

8 April 2019

Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

optic nerve morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

pronephric field specification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

metanephric mesenchymal cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

metanephric epithelium development

1 reference

8 April 2019

Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

mesenchymal to epithelial transition involved in metanephros morphogenesis

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

glial cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

transcription by RNA polymerase II

1 reference

8 April 2019

The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

retinal pigment epithelium development

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

nephric duct formation

1 reference

8 April 2019

stem cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

metanephric distal convoluted tubule development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

reactive oxygen species metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

negative regulation of mesenchymal cell apoptotic process involved in metanephros development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

mesonephros development

1 reference

8 April 2019

optic nerve structural organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

positive regulation of transcription, DNA-templated

4 references

1 January 2018

WNT5A is regulated by PAX2 and may be involved in blastemal predominant Wilms tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02962&geneProductId=UniProtKB:Q02962

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02962&geneProductId=UniProtKB:Q02962

1 January 2018

PAX2 activates WNT4 expression during mammalian kidney development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02962&geneProductId=UniProtKB:Q02962

1 January 2018

Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02962&geneProductId=UniProtKB:Q02962

cellular response to epidermal growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

metanephric nephron tubule formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

positive regulation of metanephric glomerulus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

response to nutrient levels

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

negative regulation of apoptotic process involved in metanephric nephron tubule development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

inner ear morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

cochlea morphogenesis

1 reference

8 April 2019

positive regulation of optic nerve formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

positive regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

optic cup morphogenesis involved in camera-type eye development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

urogenital system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

cell fate determination

1 reference

8 April 2019

negative regulation of programmed cell death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

vestibulocochlear nerve formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

camera-type eye development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

metanephric collecting duct development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

negative regulation of reactive oxygen species metabolic process

1 reference

8 April 2019

Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

mesodermal cell fate specification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

PAX2 oncogene negatively regulates the expression of the host defense peptide human beta defensin-1 in prostate cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

metanephric mesenchyme development

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

optic chiasma development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

optic nerve development

1 reference

8 April 2019

1 reference

8 April 2019

Further delineation of renal-coloboma syndrome in patients with extreme variability of phenotype and identical PAX2 mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

negative regulation of cytolysis

TAS

1 reference

8 April 2019

PAX2 oncogene negatively regulates the expression of the host defense peptide human beta defensin-1 in prostate cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

mesenchymal to epithelial transition

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

positive regulation of transcription, DNA-templated

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

PAX2 activates WNT4 expression during mammalian kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

8 April 2019

WNT5A is regulated by PAX2 and may be involved in blastemal predominant Wilms tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02962

1 reference

Paired-box protein 2 C-terminal

1 reference

inferred by common MeSH mappings on source and on Wikidata

Identifiers

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference