WNT5A is regulated by PAX2 and may be involved in blastemal predominant Wilms tumorigenesis (Q24320196)

GOA release 2020-03-11

Paired box 2

1 reference

positive regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Yahya Tamimi

1

0 references

Usukuma Ekuere

2

0 references

Nicholas Laughton

3

0 references

Paul Grundy

Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2

4

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language of work or name

English

0 references

publication date

December 2008

0 references

published in

Neoplasia

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volume

10

0 references

issue

12

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page(s)

1470-80

0 references

cites work

1 reference

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The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

19 March 2017

1 reference

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Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

PAX2 suppresses apoptosis in renal collecting duct cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Repression of Pax-2 by WT1 during normal kidney development

19 March 2017

1 reference

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Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

19 March 2017

1 reference

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Wnt5a regulates Shh and Fgf10 signaling during lung development

19 March 2017

1 reference

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Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus

19 March 2017

1 reference

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Expression and regulation of WNT5A and WNT5B in human cancer: up-regulation of WNT5A by TNFalpha in MKN45 cells and up-regulation of WNT5B by beta-estradiol in MCF-7 cells

19 March 2017

1 reference

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A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo

19 March 2017

1 reference

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Pax2 contributes to inner ear patterning and optic nerve trajectory

19 March 2017

1 reference

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Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor

19 March 2017

1 reference

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Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

19 March 2017

1 reference

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Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

19 March 2017

1 reference

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Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney

19 March 2017

1 reference

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Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene

19 March 2017

1 reference

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Pax-2 controls multiple steps of urogenital development

19 March 2017

1 reference

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19 March 2017

1 reference

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The cellular basis of kidney development

7 April 2017

1 reference

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Molecular cytogenetic characterization of four previously established and two newly established Ewing sarcoma cell lines.

27 September 2017

1 reference

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Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group

27 September 2017

1 reference

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Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

27 September 2017

1 reference

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National Wilms Tumor Study: an update for pathologists

27 September 2017

1 reference

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Microdissecting the genetic events in nephrogenic rests and Wilms' tumor development

27 September 2017

1 reference

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Pax genes and organogenesis.

27 September 2017

1 reference

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Pax-2, kidney development, and oncogenesis

27 September 2017

1 reference

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Identification of novel Pax-2 binding sites by chromatin precipitation

27 September 2017

1 reference

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Mutation of PAX2 in two siblings with renal-coloboma syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma

27 September 2017

1 reference

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The genetics of Wilms' tumor--a case of disrupted development

27 September 2017

1 reference

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Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

The paired box encodes a second DNA-binding domain in the paired homeo domain protein.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Wilms' tumour: reconciling genetics and biology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

A ureteric bud cell line induces nephrogenesis in two steps by two distinct signals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the caspase inhibitor, Z-VAD-fmk

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

[PAX gene function during kidney tumorigenesis: a comparative approach].

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Identification of target genes regulated by FOXC1 using nickel agarose-based chromatin enrichment

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Ureteric Bud Apoptosis and Renal Hypoplasia in Transgenic PAX2-Bax Fetal Mice Mimics the Renal-Coloboma Syndrome

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Primary renal hypoplasia in humans and mice with PAX2 mutations: evidence of increased apoptosis in fetal kidneys of Pax2(1Neu) +/- mutant mice.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586697

Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms' tumour

29 November 2018

1 reference

12 December 2020

Paired box genes, PAX-2 and PAX-8, are not frequently mutated in Wilms tumor

1 reference

12 December 2020

Methylation status of Wnt signaling pathway genes affects the clinical outcome of Philadelphia-positive acute lymphoblastic leukemia

1 reference

12 December 2020

Immunohistochemical detection of p53 protein expression as a prognostic indicator in Wilms tumor

1 reference

12 December 2020

Identifiers

DOI

10.1593/NEO.08442

1 reference

1 reference

1 reference

PubMed publication ID

19048125

1 reference