Tumor protein, translationally-controlled 1 (Q21130033)

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mammalian protein found in Homo sapiens

• histamine-releasing factor
• fortilin
• TPT1
• HRF
• p23
• translationally-controlled tumor protein
• Translationally-controlled tumor protein

edit

Language	Label	Description	Also known as
English	Tumor protein, translationally-controlled 1	mammalian protein found in Homo sapiens	histamine-releasing factor fortilin TPT1 HRF p23 translationally-controlled tumor protein Translationally-controlled tumor protein

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13693

part of

Mss4-like superfamily

2 references

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13693

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/H0YCX0

Translationally controlled tumour protein

2 references

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13693

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/H0YCX0

Mss4/translationally controlled tumour-associated TCTP

2 references

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13693

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/H0YCX0

Translationally controlled tumour protein (TCTP) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Translationally controlled tumour protein, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

image

Protein TPT1 PDB 1yz1.png
1,109 × 868; 538 KB

0 references

found in taxon

Homo sapiens

2 references

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13693

stated in

UniProt

UniProt protein ID

H0YCX0

retrieved

17 September 2016

encoded by

TPT1-AS1

2 references

stated in

UniProt

retrieved

5 December 2018

UniProt protein ID

P13693

stated in

UniProt

UniProt protein ID

H0YCX0

retrieved

20 March 2016

language of work or name

English

TPT1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13693

molecular function

calcium ion binding

determination method

IDA

2 references

retrieved

17 October 2017

stated in

The translationally controlled tumor protein is a novel calcium binding protein of the human placenta and regulates calcium handling in trophoblast cells

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IDA

retrieved

17 October 2017

stated in

Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IDA

protein binding

determination method

IPI

9 references

retrieved

8 April 2019

stated in

Anti-apoptotic protein TCTP controls the stability of the tumor suppressor p53

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

retrieved

8 April 2019

stated in

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

retrieved

8 April 2019

stated in

Characterization of the Translationally Controlled Tumor Protein (TCTP) Interactome Reveals Novel Binding Partners in Human Cancer Cells.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

retrieved

8 April 2019

stated in

Interaction between fortilin and transforming growth factor-beta stimulated clone-22 (TSC-22) prevents apoptosis via the destabilization of TSC-22

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

retrieved

8 April 2019

stated in

Inhibition of Na,K-ATPase-suppressive activity of translationally controlled tumor protein by sorting nexin 6

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

retrieved

8 April 2019

stated in

Role of the translationally controlled tumor protein in DNA damage sensing and repair

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

retrieved

8 April 2019

stated in

Translationally controlled tumor protein induces human breast epithelial cell transformation through the activation of Src

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

retrieved

8 April 2019

stated in

Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IPI

microtubule binding

determination method

IBA

1 reference

retrieved

17 October 2017

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IBA

RNA binding

determination method

IDA

1 reference

retrieved

17 October 2017

stated in

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IDA

RNA binding

determination method

HDA

1 reference

retrieved

8 April 2019

stated in

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

HDA

calcium ion binding

determination method

IBA

IDA

3 references

retrieved

8 April 2019

stated in

The translationally controlled tumor protein is a novel calcium binding protein of the human placenta and regulates calcium handling in trophoblast cells

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

retrieved

8 April 2019

stated in

Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IBA

cell component

cytoplasm

determination method

IDA

IEA

TAS

3 references

retrieved

17 October 2017

stated in

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

TAS

retrieved

17 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IEA

retrieved

17 October 2017

stated in

Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IDA

multivesicular body

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

tubulin complex

determination method

IDA

1 reference

retrieved

17 October 2017

stated in

Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IDA

extracellular exosome

determination method

IDA

1 reference

retrieved

17 October 2017

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IDA

nucleus

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Characterization of fortilin, a novel antiapoptotic protein

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

extracellular space

determination method

IDA

TAS

2 references

retrieved

8 April 2019

stated in

Molecular identification of an IgE-dependent histamine-releasing factor

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

TAS

retrieved

8 April 2019

stated in

TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

cytosol

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

spindle pole

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

cytoplasm

determination method

IBA

IDA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IEA

retrieved

8 April 2019

stated in

Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IBA

cytoplasmic microtubule

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IDA

extracellular exosome

determination method

HDA

1 reference

retrieved

8 April 2019

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

HDA

biological process

regulation of apoptotic process

determination method

NAS

1 reference

retrieved

8 April 2019

stated in

Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

NAS

response to virus

determination method

IEP

1 reference

retrieved

8 April 2019

stated in

Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IEP

cellular calcium ion homeostasis

determination method

IC

1 reference

retrieved

8 April 2019

stated in

The translationally controlled tumor protein is a novel calcium binding protein of the human placenta and regulates calcium handling in trophoblast cells

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IC

negative regulation of apoptotic process

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

TAS

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

Characterization of fortilin, a novel antiapoptotic protein

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IMP

calcium ion transport

determination method

IC

1 reference

retrieved

8 April 2019

stated in

The translationally controlled tumor protein is a novel calcium binding protein of the human placenta and regulates calcium handling in trophoblast cells

GOA

curator

UniProt

UniProt protein ID

P13693

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13693

determination method

IC

cell differentiation

determination method

IBA

1 reference

retrieved

17 October 2017

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13693&geneProductId=UniProtKB:P13693

determination method

IBA

has part(s)

Translationally controlled tumour protein, conserved site

2 references

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13693

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/H0YCX0

Translationally controlled tumour protein (TCTP) domain

2 references

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13693

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/H0YCX0

Identifiers

RefSeq protein ID

NP_001273201

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7178

NP_001273202

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7178

NP_003286

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7178

UniProt protein ID

P13693

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13693

H0YCX0

1 reference

stated in

UniProt

UniProt protein ID

H0YCX0

retrieved

20 March 2016

language of work or name

English

Ensembl protein ID

ENSP00000368344

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000368344

ENSP00000368345

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000368345

ENSP00000431872

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000431872

ENSP00000339051

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000339051

ENSP00000368350

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000368350

ENSP00000432457

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000432457

ENSP00000433091

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000433091

ENSP00000433738

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000433738

ENSP00000477781

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000477781

PDB structure ID

1YZ1

1 reference

stated in

UniProt

UniProt protein ID

P13693

retrieved

9 August 2016

language of work or name

English

3EBM

1 reference

stated in

UniProt

UniProt protein ID

P13693

retrieved

9 August 2016

language of work or name

English

4Z9V

1 reference

stated in

UniProt

UniProt protein ID

P13693

retrieved

9 August 2016

language of work or name

English

2HR9

1 reference

stated in

UniProt

UniProt protein ID

P13693

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21130033&oldid=2023011911"