Actin gamma 1 (Q21131452)

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mammalian protein found in Homo sapiens

cytoskeletal gamma-actin
ACTG1
Gamma-actin
deafness, autosomal dominant 26
epididymis luminal protein 176
deafness, autosomal dominant 20
actin, cytoplasmic 2

Language	Label	Description	Also known as
English	Actin gamma 1	mammalian protein found in Homo sapiens	cytoskeletal gamma-actin ACTG1 Gamma-actin deafness, autosomal dominant 26 epididymis luminal protein 176 deafness, autosomal dominant 20 actin, cytoplasmic 2

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P63261

Actin/actin-like conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Actin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

protein binding

determination method

6 references

31 October 2017

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

Widespread macromolecular interaction perturbations in human genetic disorders

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

ubiquitin protein ligase binding

determination method

1 reference

31 October 2017

Parkin interacts with Ambra1 to induce mitophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

identical protein binding

determination method

4 references

31 October 2017

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

Widespread macromolecular interaction perturbations in human genetic disorders

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

profilin binding

determination method

1 reference

31 October 2017

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

extracellular exosome

determination method

4 references

31 October 2017

Proteomic identification of exosomal LRG1: a potential urinary biomarker for detecting NSCLC

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

blood microparticle

determination method

1 reference

31 October 2017

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

plasma membrane

determination method

2 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

3 references

31 October 2017

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

extracellular matrix

determination method

1 reference

31 October 2017

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

extracellular space

determination method

actin cytoskeleton

determination method

1 reference

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

filamentous actin

determination method

1 reference

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

determination method

1 reference

31 October 2017

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

biological process

cell junction assembly

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

ephrin receptor signaling pathway

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

platelet aggregation

determination method

1 reference

31 October 2017

Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

Fc-gamma receptor signaling pathway involved in phagocytosis

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

retina homeostasis

determination method

1 reference

31 October 2017

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

vascular endothelial growth factor receptor signaling pathway

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

membrane organization

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

sarcomere organization

determination method

1 reference

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63261&geneProductId=UniProtKB:P63261

determination method

Actin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P63261

Actin/actin-like conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P63261

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000458162

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000458162

ENSP00000458435

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000458435

ENSP00000459124

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000459124

ENSP00000461672

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000461672

ENSP00000477968

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000477968

ENSP00000459119

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000459119

ENSP00000460464

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000460464

ENSP00000460660

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000460660

ENSP00000461407

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000461407

ENSP00000462823

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000462823

ENSP00000466346

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466346

ENSP00000493648

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000493648

PDB structure ID

1 reference

UniProt protein ID

5 August 2016

language of work or name

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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