Serpin family B member 9 (Q21134307)

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mammalian protein found in Homo sapiens

serpin peptidase inhibitor, clade B (ovalbumin), member 9
peptidase inhibitor 9
cytoplasmic antiproteinase 3
PI-9
CAP3
SERPINB9
serpin peptidase inhibitor, clade B, member 9
serpin B9
protease inhibitor 9 (ovalbumin type)
serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9
testicular tissue protein Li 180
CAP-3

Language	Label	Description	Also known as
English	Serpin family B member 9	mammalian protein found in Homo sapiens	serpin peptidase inhibitor, clade B (ovalbumin), member 9 peptidase inhibitor 9 cytoplasmic antiproteinase 3 PI-9 CAP3 SERPINB9 serpin peptidase inhibitor, clade B, member 9 serpin B9 protease inhibitor 9 (ovalbumin type) serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 testicular tissue protein Li 180 CAP-3

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptidase inhibitor activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

determination method

protease binding

determination method

1 reference

8 April 2019

The granzyme B inhibitor SERPINB9 (protease inhibitor 9) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

serine-type endopeptidase inhibitor activity

determination method

4 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

26 September 2017

The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

26 September 2017

A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

serine-type endopeptidase inhibitor activity

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

determination method

1 reference

26 September 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

intracellular anatomical structure

determination method

extracellular exosome

determination method

determination method

determination method

3 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

26 September 2017

Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

26 September 2017

The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

extracellular space

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

The granzyme B inhibitor SERPINB9 (protease inhibitor 9) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

Golgi apparatus

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

determination method

1 reference

8 April 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

collagen-containing extracellular matrix

determination method

1 reference

8 April 2019

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

biological process

negative regulation of peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

mast cell mediated immunity

determination method

1 reference

8 April 2019

The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

negative regulation of apoptotic process

determination method

2 references

protection from natural killer cell mediated cytotoxicity

determination method

1 reference

8 April 2019

The novel role of SERPINB9 in cytotoxic protection of human mesenchymal stem cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

cellular response to estrogen stimulus

determination method

1 reference

8 April 2019

Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

positive regulation of gene expression

determination method

1 reference

8 April 2019

Induction of serine protease inhibitor 9 by Mycobacterium tuberculosis inhibits apoptosis and promotes survival of infected macrophages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

negative regulation by symbiont of host apoptotic process

determination method

1 reference

8 April 2019

Induction of serine protease inhibitor 9 by Mycobacterium tuberculosis inhibits apoptosis and promotes survival of infected macrophages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

immune response

determination method

1 reference

8 April 2019

Estrogen induction of the granzyme B inhibitor, proteinase inhibitor 9, protects cells against apoptosis mediated by cytotoxic T lymphocytes and natural killer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

negative regulation of endopeptidase activity

determination method

1 reference

26 September 2017

The novel role of SERPINB9 in cytotoxic protection of human mesenchymal stem cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P50453&geneProductId=UniProtKB:P50453

determination method

apoptotic process

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50453

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P50453

Serpin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P50453

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000370074

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000370074

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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