The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells (Q22254013)

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English	The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells	scientific article

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scholarly article

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The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells (English)

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Serpin family B member 9

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GOA release 2020-03-11

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

1 reference

GOA release 2020-03-11

author name string

J L Young

1

author given names

J L

author last names

Young

1 reference

8 February 2023

G K Sukhova

2

author given names

G K

author last names

Sukhova

1 reference

8 February 2023

D Foster

3

author given names

D

author last names

Foster

1 reference

8 February 2023

W Kisiel

4

author given names

W

author last names

Kisiel

1 reference

8 February 2023

P Libby

5

author given names

P

author last names

Libby

1 reference

8 February 2023

U Schönbeck

6

author given names

U

author last names

Schönbeck

1 reference

8 February 2023

language of work or name

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publication date

1 May 2000

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Journal of Experimental Medicine

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191

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1535-44

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9

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Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9

1 reference

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19 March 2017

A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Molecular cloning of the interleukin-1 beta converting enzyme

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Atherosclerosis — An Inflammatory Disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Structure and mechanism of interleukin-1 beta converting enzyme

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Human ICE/CED-3 protease nomenclature

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

The serpin superfamily of proteinase inhibitors: structure, function, and regulation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Apoptosis in the pathogenesis and treatment of disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

19 March 2017

Expression, purification, and inhibitory properties of human proteinase inhibitor

1 reference

https://api.crossref.org/works/10.1084/JEM.191.9.1535

22 April 2017

The pathogenesis of atherosclerosis: a perspective for the 1990s

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

7 April 2017

Biologic basis for interleukin-1 in disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

7 April 2017

Room temperature-induced apoptosis of Jurkat cells sensitive to both caspase-1 and caspase-3 inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

In vitro and in vivo studies of ICE inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Inducible interleukin-1 gene expression in human vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Determination of the minimum polypeptide lengths of the functionally active sites of human interleukins 1 alpha and 1 beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Identification of a monocyte specific pre-interleukin 1 beta convertase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Functional role of interleukin 1 beta (IL-1 beta) in IL-1 beta-converting enzyme-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Interleukin-1 beta converting enzyme in murine Langerhans cells and epidermal-derived dendritic cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

27 September 2017

Interleukin-18: perspectives on the newest interleukin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

30 May 2018

Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

30 May 2018

Overview of interleukin-18: more than an interferon-gamma inducing factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

30 May 2018

Role of pro- and anti-inflammatory cytokines during inflammation: experimental and clinical findings

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

30 May 2018

Human vascular smooth muscle cells express interleukin-1beta-converting enzyme (ICE), but inhibit processing of the interleukin-1beta precursor by ICE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

30 May 2018

Localization of interleukin-1 beta converting enzyme mRNA in rat brain vasculature: evidence that the genes encoding the interleukin-1 system are constitutively expressed in brain blood vessels. Pathophysiological implications.

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30 May 2018

Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

30 May 2018

Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

30 May 2018

Structure-function mapping of interleukin 1 precursors. Cleavage leads to a conformational change in the mature protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

30 May 2018

Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

29 November 2018

Relation of plaque lipid composition and morphology to the stability of human aortic plaques.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

29 November 2018

The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213432

29 November 2018

Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the synthesis and kinetics of release of interleukin 1 alpha, interleukin 1 beta and tumor necrosis factor from human mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of interleukin-1 beta by a co-induced protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1 beta precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression, Purification, and Inhibitory Properties of Human Proteinase Inhibitor 8

1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Culture of quiescent arterial smooth muscle cells in a defined serum-free medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10790428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Cloning, Expression, and Partial Characterization of Two Novel Members of the Ovalbumin Family of Serine Proteinase Inhibitors

1 reference

https://api.crossref.org/works/10.1084%2FJEM.191.9.1535

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1084/JEM.191.9.1535

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