A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling (Q21142769)

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A Lentivirus-Mediated Genetic Screen Identifies Dihydrofolate Reductase (DHFR) as a Modulator of β-Catenin/GSK3 Signaling

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English	A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling	scientific article	A Lentivirus-Mediated Genetic Screen Identifies Dihydrofolate Reductase (DHFR) as a Modulator of β-Catenin/GSK3 Signaling

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scholarly article

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A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling (English)

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Xiaohua Douglas Zhang

object named as

Xiaohua Douglas Zhang

8

author given names

Xiaohua Douglas

author last names

Zhang

1 reference

17 August 2022

Randall T. Moon

object named as

Randall T Moon

10

author given names

Randall T

author last names

Moon

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17 August 2022

author name string

Richard A Klinghoffer

1

author given names

Richard A

author last names

Klinghoffer

1 reference

17 August 2022

Jason Frazier

2

author given names

Jason

author last names

Frazier

1 reference

17 August 2022

James Annis

3

author given names

James

author last names

Annis

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17 August 2022

Jason D Berndt

4

author given names

Jason D

author last names

Berndt

1 reference

17 August 2022

Brian S Roberts

5

author given names

Brian S

author last names

Roberts

1 reference

17 August 2022

William T Arthur

6

author given names

William T

author last names

Arthur

1 reference

17 August 2022

Raul Lacson

7

author given names

Raul

author last names

Lacson

1 reference

17 August 2022

Marc Ferrer

9

author given names

Marc

author last names

Ferrer

1 reference

17 August 2022

Michele A Cleary

11

author given names

Michele A

author last names

Cleary

1 reference

17 August 2022

language of work or name

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publication date

2009

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4

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e6892

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9

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copyright license

Creative Commons Attribution 4.0 International

3 September 2009

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April 2022 Public Data File from Crossref

copyright status

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Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics

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A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

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19 March 2017

Wnt/beta-catenin signaling in development and disease

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19 March 2017

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

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19 March 2017

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

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19 March 2017

Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

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Novel analytic criteria and effective plate designs for quality control in genome-scale RNAi screens

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19 March 2017

Integrating experimental and analytic approaches to improve data quality in genome-wide RNAi screens

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19 March 2017

beta-catenin destruction complex: insights and questions from a structural perspective

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19 March 2017

Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6.

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19 March 2017

The functional human dihydrofolate reductase gene

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19 March 2017

Identification of FAP locus genes from chromosome 5q21

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19 March 2017

beta-catenin is a target for the ubiquitin-proteasome pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731218

7 April 2017

WNT and beta-catenin signalling: diseases and therapies

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7 April 2017

The glamour and gloom of glycogen synthase kinase-3

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7 April 2017

Caught up in a Wnt storm: Wnt signaling in cancer

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7 April 2017

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

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7 April 2017

Identification and characterization of the familial adenomatous polyposis coli gene

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Determination of sample size in genome-scale RNAi screens

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12 September 2017

A unified approach to false discovery rate estimation

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12 September 2017

Incidence of melanoma and other malignancies among rheumatoid arthritis patients treated with methotrexate

1 reference

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12 September 2017

An optimized lentivirus-mediated RNAi screen reveals kinase modulators of kinesin-5 inhibitor sensitivity

1 reference

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12 September 2017

A new method with flexible and balanced control of false negatives and false positives for hit selection in RNA interference high-throughput screening assays

1 reference

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12 September 2017

Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions

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Robust statistical methods for hit selection in RNA interference high-throughput screening experiments

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Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

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The promise of genomics to identify novel therapeutic targets

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Molecular mechanism of methotrexate action in inflammation

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Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

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Folic acid reduces nuclear translocation of beta-catenin in rectal mucosal crypts of patients with colorectal adenomas

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19727391

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0006892

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2009PLoSO...4.6892K

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