Of mice, cattle, and humans: the immunology and treatment of river blindness (Q21144551)

inferred from abstract

3

Odile Bain

Odile

Bain

1 reference

16 August 2022

Judith E Allen

1

Judith E

Allen

1 reference

16 August 2022

10

Samuel Wanji

Samuel

Wanji

1 reference

16 August 2022

4

Achim Hoerauf

Achim

Hoerauf

1 reference

16 August 2022

2

Ohene Adjei

Ohene

Adjei

1 reference

16 August 2022

Wolfgang H Hoffmann

5

Wolfgang H

Hoffmann

1 reference

16 August 2022

Benjamin L Makepeace

6

Benjamin L

Makepeace

1 reference

16 August 2022

Hartwig Schulz-Key

7

Hartwig

Schulz-Key

1 reference

16 August 2022

Vincent N Tanya

8

Vincent N

Tanya

1 reference

16 August 2022

Alexander J Trees

9

Alexander J

Trees

1 reference

16 August 2022

David W Taylor

11

David W

PLoS Neglected Tropical Diseases

Taylor

1 reference

16 August 2022

language of work or name

English

0 references

publication date

30 April 2008

10 references

23 March 2019

25 April 2019

20 June 2019

22 June 2019

22 October 2019

11 November 2019

27 May 2020

24 July 2020

24 September 2020

27 June 2022

10 references

23 March 2019

25 April 2019

20 June 2019

22 June 2019

22 October 2019

11 November 2019

27 May 2020

24 July 2020

24 September 2020

27 June 2022

2

0 references

page(s)

e217

0 references

issue

4

0 references

copyright license

Creative Commons Attribution 2.5 Generic

0 references

Creative Commons Attribution 4.0 International

10 references

23 March 2019

25 April 2019

20 June 2019

22 June 2019

22 October 2019

11 November 2019

27 May 2020

24 July 2020

24 September 2020

on focus list of Wikimedia project

27 June 2022

copyright status

copyrighted

0 references

ScienceSource

0 references

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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Down-regulated lymphoproliferation coincides with parasite maturation and with the collapse of both gamma interferon and interleukin-4 responses in a bovine model of onchocerciasis

12 September 2017

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Neutrophil accumulation around Onchocerca worms and chemotaxis of neutrophils are dependent on Wolbachia endobacteria

12 September 2017

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12 September 2017

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Depletion of wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment

12 September 2017

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Interleukin-4 is essential for the control of microfilariae in murine infection with the filaria Litomosoides sigmodontis

12 September 2017

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IL-5 is essential for vaccine-induced protection and for resolution of primary infection in murine filariasis

12 September 2017

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Analysis of genes expressed at the infective larval stage validates utility of Litomosoides sigmodontis as a murine model for filarial vaccine development

12 September 2017

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12 September 2017

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Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift

12 September 2017

1 reference

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Parasitology and immunology of mice vaccinated with irradiated Litomosoides sigmodontis larvae

12 September 2017

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Tetracycline therapy targets intracellular bacteria in the filarial nematode Litomosoides sigmodontis and results in filarial infertility

12 September 2017

1 reference

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Early reduction of the challenge recovery rate following immunization with irradiated infective larvae in a filaria mouse system

12 September 2017

1 reference

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12 September 2017

1 reference

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Maturation of the filariaLitomosoides sigmodontisin BALB/c mice; comparative susceptibility of nine other inbred strains

12 September 2017

1 reference

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Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

12 September 2017

1 reference

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Immunoglobulin E and eosinophil-dependent protective immunity to larval Onchocerca volvulus in mice immunized with irradiated larvae.

27 September 2017

1 reference

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Epidemiology of concomitant infections due to Loa loa, Mansonella perstans, and Onchocerca volvulus in rain forest villages of Cameroon

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Wolbachia- and Onchocerca volvulus-induced keratitis (river blindness) is dependent on myeloid differentiation factor 88

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Regulatory T cells modulate Th2 responses induced by Brugia pahangi third-stage larvae

30 May 2018

1 reference

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An investigation of persistent microfilaridermias despite multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Mapping the presence of Wolbachia pipientis on the phylogeny of filarial nematodes: evidence for symbiont loss during evolution

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Immunity to Onchocerca volvulus microfilariae in mice and the induction of cross-protection with O. lienalis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients.

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

Evidence for macrofilaricidal activity of ivermectin against female Onchocerca volvulus: further analysis of a clinical trial in the Republic of Cameroon indicating two distinct killing mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

Thirty-month follow-up of sub-optimal responders to multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

The migration and localization of Loa loa infective and fourth-stage larvae in normal and immunosuppressed rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

Quantitative appraisal of murine filariasis confirms host strain differences but reveals that BALB/c females are more susceptible than males to Litomosoides sigmodontis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

IL-4 is required to prevent filarial nematode development in resistant but not susceptible strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

Interleukin-4 influences the production of microfilariae in a mouse model of Brugia infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

Most of the response elicited against Wolbachia surface protein in filarial nematode infection is due to the infective larval stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

Endosymbiotic bacteria in worms as targets for a novel chemotherapy in filariasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0000217

Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

CTLA-4 and CD4+ CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

F4/80+ alternatively activated macrophages control CD4+ T cell hyporesponsiveness at sites peripheral to filarial infection

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

CTLA-4 in filarial infections: implications for a role in diminished T cell reactivity

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent relationship

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Vaccination of Jirds, Meriones unguiculatus, against Litomosoides carinii and Brugia pahangi using irradiate larvae of L. carinii.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323618

Immunization of calves against the microfilariae of Onchocerca lienalis

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18446236

12 December 2020

inferred from PubMed ID database lookup

Larval biology of six filariae of the sub-family Onchocercinae in a vertebrate host

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18446236

12 December 2020

inferred from PubMed ID database lookup

Meeting of the International Task Force for Disease Eradication--11 January 2007

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12 December 2020

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Identifiers

DOI

10.1371/JOURNAL.PNTD.0000217

1 reference

2115222

2115222

1 reference

1 reference

1 reference