Immune regulation by helminth parasites: cellular and molecular mechanisms (Q28204460)

T cell responsiveness correlates differentially with antibody isotype levels in clinical and asymptomatic filariasis

31 March 2020

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Antigen-specific proliferation and interferon-gamma and interleukin-5 production are down-regulated during Schistosoma haematobium infection

31 March 2020

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Impairment of tetanus toxoid-specific Th1-like immune responses in humans infected with Schistosoma mansoni.

31 March 2020

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Impaired tetanus-specific cellular and humoral responses following tetanus vaccination in human onchocerciasis: a possible role for interleukin-10

31 March 2020

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Prolongation of allograft survival by Nippostrongylus brasiliensis is associated with decreased allospecific cytotoxic T lymphocyte activity and development of T cytotoxic cell type 2 cells

31 March 2020

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Transmission intensity determines lymphocyte responsiveness and cytokine bias in human lymphatic filariasis

31 March 2020

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Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy

31 March 2020

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Helminth infections are associated with protection from malaria-related acute renal failure and jaundice in Thailand.

31 March 2020

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Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10

31 March 2020

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Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease

31 March 2020

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Allergy, parasites, and the hygiene hypothesis

31 March 2020

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Regulation of immunity to parasites by T cells and T cell-derived cytokines

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Immunological modulation and evasion by helminth parasites in human populations

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Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

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The immunobiology of schistosomiasis

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The L3 of Brugia induces a Th2-polarized response following activation of an IL-4-producing CD4-CD8- alphabeta T cell population

31 March 2020

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Nippostrongylus brasiliensis can induce B7-independent antigen-specific development of IL-4-producing T cells from naive CD4 T cells in vivo

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Cytokine-mediated regulation of chronic intestinal helminth infection

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Human IgE, IgG4 and resistance to reinfection with Schistosoma haematobium

31 March 2020

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Immunity to onchocerciasis: putative immune persons produce a Th1-like response to Onchocerca volvulus

31 March 2020

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Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models.

31 March 2020

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Parasite immunity: Pathways for expelling intestinal helminths

31 March 2020

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IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.

31 March 2020

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The effect of nematode infection upon intestinal smooth muscle function

31 March 2020

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Cutting edge: IL-4 receptor expression by non-bone marrow-derived cells is required to expel gastrointestinal nematode parasites.

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Role of IL-5 in innate and adaptive immunity to larval Strongyloides stercoralis in mice

31 March 2020

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Do eosinophils have a role in the killing of helminth parasites?

31 March 2020

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Th1-Th2: reliable paradigm or dangerous dogma?

31 March 2020

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Tumor necrosis factor alpha is a critical component of interleukin 13-mediated protective T helper cell type 2 responses during helminth infection

31 March 2020

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IL-4-regulated enteropathy in an intestinal nematode infection

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Cytokine Interaction and Immune Responses during Schistosoma mansoni Infection

31 March 2020

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IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis

31 March 2020

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Cytokine-mediated host responses during schistosome infections; walking the fine line between immunological control and immunopathology

31 March 2020

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Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

31 March 2020

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CD4+ CD25+ suppressor T cells: more questions than answers

31 March 2020

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Immunology of parasitic helminth infections

31 March 2020

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Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent

31 March 2020

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Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study

31 March 2020

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T-cell activation and the balance of antibody isotypes in human lymphatic filariasis.

31 March 2020

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Depression of antigen-specific interleukin-5 and interferon-gamma responses in human lymphatic filariasis as a function of clinical status and age.

31 March 2020

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Early human infection with Onchocerca volvulus is associated with an enhanced parasite-specific cellular immune response

31 March 2020

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Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response

31 March 2020

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IL-4 is required to prevent filarial nematode development in resistant but not susceptible strains of mice

31 March 2020

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Immunological tolerance: The key feature in human filariasis?

31 March 2020

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Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection

31 March 2020

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IL-10 is critical for host resistance and survival during gastrointestinal helminth infection.

31 March 2020

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IL-10 is crucial for the transition from acute to chronic disease state during infection of mice with Schistosoma mansoni.

31 March 2020

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High levels of spontaneous and parasite antigen-driven interleukin-10 production are associated with antigen-specific hyporesponsiveness in human lymphatic filariasis

31 March 2020

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Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift

31 March 2020

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Evidence of a T helper type 2 activation in human schistosomiasis

31 March 2020

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The effect of anti-IL-10 on proliferation and cytokine production in human schistosomiasis: fresh versus cryopreserved cells

31 March 2020

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Antigen-specific T regulatory-1 cells are associated with immunosuppression in a chronic helminth infection (onchocerciasis).

31 March 2020

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CTLA-4 in filarial infections: implications for a role in diminished T cell reactivity

31 March 2020

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Natural versus adaptive regulatory T cells

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Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora

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Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases

31 March 2020

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Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussi

31 March 2020

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CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

31 March 2020

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Dendritic cells as sensors of infection.

31 March 2020

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Antigen-specific suppressor cells and suppressor factors in human filariasis with Brugia malayi

31 March 2020

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Divergent roles for macrophages in lymphatic filariasis.

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Profound suppression of cellular proliferation mediated by the secretions of nematodes

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IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype

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Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro.

31 March 2020

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Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact

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APC from mice harbouring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production

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Alternative activation of macrophages

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Th1- and Th2-cell commitment during infectious disease: asymmetry in divergent pathways

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CD8- dendritic cell activation status plays an integral role in influencing Th2 response development

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Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals

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CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1

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Cutting edge: polarized Th cell response induction by transferred antigen-pulsed dendritic cells is dependent on IL-4 or IL-12 production by recipient cells

31 March 2020

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Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites

31 March 2020

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A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization

31 March 2020

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Parasitic helminth genomics. Filarial Genome Project

31 March 2020

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Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.

31 March 2020

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Modulation of human T cell responses and macrophage functions by onchocystatin, a secreted protein of the filarial nematode Onchocerca volvulus

31 March 2020

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Nippocystatin, a cysteine protease inhibitor from Nippostrongylus brasiliensis, inhibits antigen processing and modulates antigen-specific immune response

31 March 2020

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Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells.

31 March 2020

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A filarial cysteine protease inhibitor down-regulates T cell proliferation and enhances interleukin-10 production

31 March 2020

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Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity

31 March 2020

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Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection

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PGE2 generation and release by the larval stage of the cestode, taenia taeniaeformis

31 March 2020

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Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae

31 March 2020

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A schistosome-expressed immunomodulatory glycoconjugate expands peritoneal Gr1(+) macrophages that suppress naive CD4(+) T cell proliferation via an IFN-gamma and nitric oxide-dependent mechanism

31 March 2020

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The schistosome oligosaccharide lacto-N-neotetraose expands Gr1(+) cells that secrete anti-inflammatory cytokines and inhibit proliferation of naive CD4(+) cells: a potential mechanism for immune polarization in helminth infections

31 March 2020

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A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells

31 March 2020

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The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.

31 March 2020

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Helminth C-type lectins and host-parasite interactions

31 March 2020

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A novel member of the transforming growth factor-beta (TGF-beta) superfamily from the filarial nematodes Brugia malayi and B. pahangi

31 March 2020

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Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi

31 March 2020

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A member of the TGF-beta receptor gene family in the parasitic nematode Brugia pahangi.

31 March 2020

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A divergent member of the transforming growth factor beta receptor family from Schistosoma mansoni is expressed on the parasite surface membrane.

31 March 2020

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Rapid purification and characterization of L-dopachrome-methyl ester tautomerase (macrophage-migration-inhibitory factor) from Trichinella spiralis, Trichuris muris and Brugia pahangi

31 March 2020

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Homologues of human macrophage migration inhibitory factor from a parasitic nematode. Gene cloning, protein activity, and crystal structure.

31 March 2020

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Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

31 March 2020

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A Brugia malayi homolog of macrophage migration inhibitory factor reveals an important link between macrophages and eosinophil recruitment during nematode infection.

31 March 2020

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Production of an interferon-gamma homologue by an intestinal nematode: functionally significant or interesting artefact?

31 March 2020

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Ascaris suum-derived products induce human neutrophil activation via a G protein-coupled receptor that interacts with the interleukin-8 receptor pathway

31 March 2020

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Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo.

31 March 2020

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Serine proteinase inhibitors from nematodes and the arms race between host and pathogen

31 March 2020

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Receptor for Fc on the surfaces of schistosomes.

31 March 2020

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Resistance of filarial nematode parasites to oxidative stress.

31 March 2020

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Suppression of secreted acetylcholinesterase expression in Nippostrongylus brasiliensis by RNA interference

31 March 2020

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Use of RNA interference to investigate gene function in the human filarial nematode parasite Brugia malayi.

31 March 2020

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Using RNA interference to manipulate endogenous gene expression in Schistosoma mansoni sporocysts.

31 March 2020

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Lack of DNA methylation in Schistosoma mansoni

31 March 2020

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A Toll-like receptor recognizes bacterial DNA

31 March 2020

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Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses.

31 March 2020

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Core alpha1-->3-fucose is a common modification of N-glycans in parasitic helminths and constitutes an important epitope for IgE from Haemonchus contortus infected sheep

31 March 2020

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Schistosome N-glycans containing core alpha 3-fucose and core beta 2-xylose epitopes are strong inducers of Th2 responses in mice

31 March 2020

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Molecular characterization of an interleukin-4-inducing factor from Schistosoma mansoni eggs

31 March 2020

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Cloning and characterization of a calcium-binding, histamine-releasing protein from Schistosoma mansoni

31 March 2020

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Lacto-N-fucopentaose III found on Schistosoma mansoni egg antigens functions as adjuvant for proteins by inducing Th2-type response

31 March 2020

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Idiotypes expressed early in experimental Schistosoma mansoni infections predict clinical outcomes of chronic disease

31 March 2020

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Long-term effect of prenatal exposure to maternal microfilaraemia on immune responsiveness to filarial parasite antigens

31 March 2020

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The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness

31 March 2020

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Do antioxidants play a role in schistosome host-parasite interactions?

31 March 2020

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Filarial nematode parasites secrete a homologue of the human cytokine macrophage migration inhibitory factor

31 March 2020

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