Ribosomal protein S3 (Q21171526)

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mammalian protein found in Homo sapiens
  • RPS3
  • small ribosomal subunit protein uS3
  • IMR-90 ribosomal protein S3
  • 40S ribosomal protein S3
edit
Language Label Description Also known as
English
Ribosomal protein S3
mammalian protein found in Homo sapiens
  • RPS3
  • small ribosomal subunit protein uS3
  • IMR-90 ribosomal protein S3
  • 40S ribosomal protein S3

Statements

molecular function
protein binding
determination method
IPI
19 references
retrieved
8 April 2019
stated in
ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Cytoplasmic ribosomal protein S3 (rpS3) plays a pivotal role in mitochondrial DNA damage surveillance
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Ribosomal protein S3 interacts with TRADD to induce apoptosis through caspase dependent JNK activation
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Ribosomal protein S3 interacts with the NF-κB inhibitor IκBα
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Ribosomal proteins are targets for the NEDD8 pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Caspase-3 cleaved p65 fragment dampens NF-κB-mediated anti-apoptotic transcription by interfering with the p65/RPS3 interaction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
retrieved
8 April 2019
stated in
Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IPI
DNA-(apurinic or apyrimidinic site) endonuclease activity
determination method
IDA
IEA
7 references
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IEA
retrieved
17 October 2017
stated in
Interactions of human ribosomal protein S3 with undamaged and damaged DNA
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
PKCdelta-dependent functional switch of rpS3 between translation and DNA repair
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
Characterization of a wide range base-damage-endonuclease activity of mammalian rpS3
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
Implication of mammalian ribosomal protein S3 in the processing of DNA damage
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
damaged DNA binding
determination method
IBA
IDA
5 references
retrieved
8 April 2019
stated in
Translocation of human ribosomal protein S3 to sites of DNA damage is dependant on ERK-mediated phosphorylation following genotoxic stress
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Characterization of human ribosomal protein S3 binding to 7,8-dihydro-8-oxoguanine and abasic sites by surface plasmon resonance
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Interactions of human ribosomal protein S3 with undamaged and damaged DNA
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IBA
DNA-(apurinic or apyrimidinic site) endonuclease activity
determination method
IBA
IDA
6 references
retrieved
1 January 2018
stated in
The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
1 January 2018
stated in
Characterization of a wide range base-damage-endonuclease activity of mammalian rpS3
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
1 January 2018
stated in
Interactions of human ribosomal protein S3 with undamaged and damaged DNA
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
1 January 2018
stated in
Implication of mammalian ribosomal protein S3 in the processing of DNA damage
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
1 January 2018
stated in
PKCdelta-dependent functional switch of rpS3 between translation and DNA repair
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IBA
DNA-(apurinic or apyrimidinic site) endonuclease activity
determination method
IBA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IEA
retrieved
8 April 2019
stated in
PKCdelta-dependent functional switch of rpS3 between translation and DNA repair
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Interactions of human ribosomal protein S3 with undamaged and damaged DNA
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Characterization of a wide range base-damage-endonuclease activity of mammalian rpS3
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Implication of mammalian ribosomal protein S3 in the processing of DNA damage
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IBA
cell component
nucleus
determination method
IDA
IEA
IMP
10 references
retrieved
17 October 2017
stated in
Ribosomal protein S3 is phosphorylated by Cdk1/cdc2 during G2/M phase
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IMP
retrieved
17 October 2017
stated in
IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IMP
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IEA
retrieved
17 October 2017
stated in
Arginine methylation of ribosomal protein S3 affects ribosome assembly
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
RpS3, a DNA repair endonuclease and ribosomal protein, is involved in apoptosis
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
Translocation of human ribosomal protein S3 to sites of DNA damage is dependant on ERK-mediated phosphorylation following genotoxic stress
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
PKCdelta-dependent functional switch of rpS3 between translation and DNA repair
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
17 October 2017
stated in
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23396&geneProductId=UniProtKB:P23396
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
IMP
11 references
retrieved
8 April 2019
stated in
Ribosomal protein S3 is phosphorylated by Cdk1/cdc2 during G2/M phase
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IMP
retrieved
8 April 2019
stated in
IKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IEA
retrieved
8 April 2019
stated in
Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
RpS3, a DNA repair endonuclease and ribosomal protein, is involved in apoptosis
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
PKCdelta-dependent functional switch of rpS3 between translation and DNA repair
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Arginine methylation of ribosomal protein S3 affects ribosome assembly
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Translocation of human ribosomal protein S3 to sites of DNA damage is dependant on ERK-mediated phosphorylation following genotoxic stress
GOA
curator
UniProt
UniProt protein ID
P23396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23396
determination method
IBA
biological process

Identifiers

Ensembl protein ID
PDB structure ID
 
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