IgVH genes from different anatomical regions, with different histopathological patterns, of a rheumatoid arthritis patient suggest cyclic re-entry of mature synovial B-cells in the hypermutation process (Q21195682)

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English	IgVH genes from different anatomical regions, with different histopathological patterns, of a rheumatoid arthritis patient suggest cyclic re-entry of mature synovial B-cells in the hypermutation process	scientific article

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1 November 2019

IgVH genes from different anatomical regions, with different histopathological patterns, of a rheumatoid arthritis patient suggest cyclic re-entry of mature synovial B-cells in the hypermutation process (English)

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1 November 2019

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rheumatoid arthritis

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Margarida M Souto-Carneiro

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M M Souto-Carneiro

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M M

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Souto-Carneiro

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1 November 2019

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V Krenn

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Krenn

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1 November 2019

R Hermann

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Hermann

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1 November 2019

A König

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König

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1 November 2019

H K Müller-Hermelink

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H K

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Müller-Hermelink

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1 November 2019

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19 May 2000

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1 November 2019

Arthritis Research

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1 November 2019

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1 November 2019

4

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1 November 2019

303-314

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1 November 2019

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

19 March 2017

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

19 March 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

2 references

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19 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

Structural insights into the evolution of an antibody combining site

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

19 March 2017

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

19 March 2017

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

19 March 2017

Histopathology and molecular pathology of synovial B-lymphocytes in rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

The structural basis of germline-encoded VH3 immunoglobulin binding to staphylococcal protein A

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

Staphylococcal protein A induces biased production of Ig by VH3-expressing B lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

12 September 2017

Clonal selection and learning in the antibody system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

Cyclic re-entry of germinal center B cells and the efficiency of affinity maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

The maturation of the immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

Where transcription meets repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

Somatic hypermutation: how many mechanisms diversify V region sequences?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

Somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

Mutation drift and repertoire shift in the maturation of the immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

Immortalized B-lymphocytes from rheumatoid synovial tissue show specificity for bacterial HSP 60.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

27 September 2017

Plasma cell development in synovial germinal centers in patients with rheumatoid and reactive arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

30 May 2018

A novel monospecific IgG2/lambda-autoantibody with specificity for a mitochondrial antigen: evidence for an antigen-driven pathogenetic B-cell response in rheumatoid synovial tissue, induced by tissue alteration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

30 May 2018

B-cell activation and development within chronically inflamed synovium in rheumatoid and reactive arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

30 May 2018

Detection of clonal B cell populations in paraffin-embedded tissues by polymerase chain reaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

30 May 2018

Staphylococcal enterotoxin A induces survival of VH3-expressing human B cells by binding to the VH region with low affinity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

29 November 2018

Low antigen dose favours selection of somatic mutants with hallmarks of antibody affinity maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

29 November 2018

Base-specific sequences that bias somatic hypermutation deduced by analysis of out-of-frame human IgVH genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

29 November 2018

Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

29 November 2018

Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

29 November 2018

The B lymphocyte in rheumatoid arthritis: analysis of rearranged Vx genes from B cells infiltrating the synovial membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17813

29 November 2018

Ancient weapons: NK-lysin, is a mammalian homolog to pore-forming peptides of a protozoan parasite

1 reference

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29 November 2018

A simplified twenty-eight-joint quantitative articular index in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral human CD5+ and CD5- B cells may express somatically mutated VH5- and VH6-encoded IgM receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The identification of germinal centres and follicular dendritic cell networks in rheumatoid synovial tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical analysis of proliferating and antigen-presenting cells in rheumatoid synovial tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal analysis of immunoglobulin mRNA in rheumatoid arthritis synovium: characterization of expanded IgG3 populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in mutational patterns between rheumatoid factors in health and disease are related to variable heavy chain family and germ-line gene usage

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delineation of selective influences shaping the mutated expressed human Ig heavy chain repertoire

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IMGT, the international ImMunoGeneTics database

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular analysis of rheumatoid factor (RF)-negative B cell hybridomas from rheumatoid synovial tissue: evidence for an antigen-induced stimulation with selection of high mutated IgVH and low mutated IgVL/lambda genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The B lymphocyte in rheumatoid arthritis: recirculation of B lymphocytes between different joints and blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/11056671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 November 2019

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1 November 2019

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