CTR9 homolog, Paf1/RNA polymerase II complex component (Q21498235)

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mammalian protein found in Mus musculus

p150TSP
TPR-containing, SH2-binding phosphoprotein of 150 kDa
tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa
Ctr9
SH2 domain binding protein 1 (tetratricopeptide repeat containing)
RNA polymerase-associated protein CTR9 homolog
SH2 domain-binding protein 1
Ctr9, Paf1/RNA polymerase II complex component, homolog

Language	Label	Description	Also known as
English	CTR9 homolog, Paf1/RNA polymerase II complex component	mammalian protein found in Mus musculus	p150TSP TPR-containing, SH2-binding phosphoprotein of 150 kDa tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa Ctr9 SH2 domain binding protein 1 (tetratricopeptide repeat containing) RNA polymerase-associated protein CTR9 homolog SH2 domain-binding protein 1 Ctr9, Paf1/RNA polymerase II complex component, homolog

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Tetratricopeptide-like helical domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62018

RNA polymerase-associated protein Ctr9

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62018

Tetratricopeptide repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tetratricopeptide repeat family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

SH2 domain binding

determination method or standard

1 reference

14 February 2019

p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

RNA polymerase II complex binding

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

protein binding

determination method or standard

3 references

14 February 2019

Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

determination method or standard

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

Cdc73/Paf1 complex

determination method or standard

4 references

11 October 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62018&geneProductId=UniProtKB:Q62018

determination method or standard

11 October 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62018&geneProductId=UniProtKB:Q62018

determination method or standard

11 October 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62018&geneProductId=UniProtKB:Q62018

determination method or standard

11 October 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62018&geneProductId=UniProtKB:Q62018

determination method or standard

Cdc73/Paf1 complex

determination method or standard

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

biological process

Wnt signaling pathway

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

trophectodermal cell differentiation

determination method or standard

1 reference

14 February 2019

CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

receptor signaling pathway via JAK-STAT

determination method or standard

1 reference

14 February 2019

hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62018&geneProductId=UniProtKB:Q62018

determination method or standard

endodermal cell fate commitment

determination method or standard

1 reference

14 February 2019

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

cellular response to lipopolysaccharide

determination method or standard

1 reference

14 February 2019

hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

regulation of genetic imprinting

determination method or standard

1 reference

14 February 2019

CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

1 reference

14 February 2019

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

interleukin-6-mediated signaling pathway

determination method or standard

1 reference

14 February 2019

hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

inner cell mass cell differentiation

determination method or standard

1 reference

14 February 2019

CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

histone H3-K4 trimethylation

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

stem cell population maintenance

determination method or standard

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

positive regulation of histone H3-K4 methylation

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

positive regulation of histone H3-K79 methylation

determination method or standard

blastocyst growth

determination method or standard

2 references

14 February 2019

CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

14 February 2019

CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

negative regulation of myeloid cell differentiation

determination method or standard

positive regulation of transcription elongation from RNA polymerase II promoter

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

histone modification

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

regulation of histone H3-K4 methylation

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

blastocyst hatching

determination method or standard

1 reference

14 February 2019

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62018

determination method or standard

tetratricopeptide repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62018

Tetratricopeptide repeat-containing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62018

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000005749

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000005749

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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