Amyloid beta (A4) precursor protein-binding, family B, member 1 (Q21498719)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

transcription factor binding

1 reference

24 April 2018

Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

24 April 2018

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

6 references

14 February 2019

Megalin interacts with APP and the intracellular adapter protein FE65 in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

histone acetyltransferase binding

IPI

1 reference

14 February 2019

Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

proline-rich region binding

NAS

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

protein-containing complex binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

1 January 2018

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

transcription factor binding

ubiquitin protein ligase binding

IDA

1 reference

1 January 2018

Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

24 April 2018

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

3 references

2 references

2 references

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

24 April 2018

Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

24 April 2018

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

2 references

protein-containing complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

postsynaptic membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

perinuclear region of cytoplasm

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

growth cone lamellipodium

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

growth cone filopodium

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

Schaffer collateral - CA1 synapse

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

24 April 2018

Isoform-specific knockout of FE65 leads to impaired learning and memory

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

negative regulation of neuron differentiation

IMP

1 reference

14 February 2019

A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

IMP

protein stabilization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

extracellular matrix organization

NAS

1 reference

14 February 2019

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

actin filament-based movement

IGI

1 reference

14 February 2019

Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

transcription, DNA-templated

NAS

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QXJ1&geneProductId=UniProtKB:Q9QXJ1

cellular response to DNA damage stimulus

IEA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

14 February 2019

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

positive regulation of transcription, DNA-templated

IGI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

negative regulation of cell growth

1 reference

14 February 2019

Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

negative regulation of transcription by RNA polymerase II

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

chromatin organization

1 reference

14 February 2019

positive regulation of neuron projection development

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

histone H4 acetylation

positive regulation of protein secretion

ISS

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXJ1

regulation of transcription, DNA-templated