osimertinib (Q21506464)

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chemical compound, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, used as a medication to treat non-small-cell lung carcinomas with a specific mutation
  • AZD 9291
  • AZD-9291
  • AZD9291
  • mereletinib (obsolete INN)
  • Tagrisso®
  • Osimertinib
  • Mereletinib
  • N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
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Language Label Description Also known as
English
osimertinib
chemical compound, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, used as a medication to treat non-small-cell lung carcinomas with a specific mutation
  • AZD 9291
  • AZD-9291
  • AZD9291
  • mereletinib (obsolete INN)
  • Tagrisso®
  • Osimertinib
  • Mereletinib
  • N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide

Statements

has use
medication
0 references
chemical structure
Osimertinib.svg
512 × 302; 6 KB
0 references
mass
499.27 dalton
1 reference
stated in
PubChem
PubChem CID
71496458
language of work or name
English
title
AZD-9291 (English)
retrieved
19 October 2016
chemical formula
C₂₈H₃₃N₇O₂
1 reference
stated in
PubChem
PubChem CID
71496458
language of work or name
English
title
AZD-9291 (English)
retrieved
20 November 2016
canonical SMILES
CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC
1 reference
stated in
PubChem
PubChem CID
71496458
language of work or name
English
title
AZD-9291 (English)
retrieved
20 November 2016
Commons category
Osimertinib
0 references

Identifiers

Reaxys registry number
23334373
1 reference
stated in
ChEBI
ChEBI ID
90943
language of work or name
English
title
osimertinib (English)
retrieved
19 October 2016
LiverTox ID
Osimertinib
0 references
ATC code
L01XE35
0 references
KEGG ID
D10766
0 references
PDB ligand ID
YY3
0 references
 
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