Mismatch repair endonuclease PMS2 (Q21980091)

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mouse protein (annotated by UniProtKB/Swiss-Prot P54279)
  • PMS1 protein homolog 2
  • DNA mismatch repair protein PMS2
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Language Label Description Also known as
English
Mismatch repair endonuclease PMS2
mouse protein (annotated by UniProtKB/Swiss-Prot P54279)
  • PMS1 protein homolog 2
  • DNA mismatch repair protein PMS2

Statements

instance of
protein
0 references
molecular function
cell component
biological process
DNA mismatch repair
determination method
ISS
IEA
IGI
IMP
TAS
ISO
12 references
retrieved
24 April 2018
stated in
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
TAS
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P54279
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
ISS
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
ISO
retrieved
24 April 2018
stated in
Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
24 April 2018
stated in
Different mutator phenotypes in Mlh1- versus Pms2-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
24 April 2018
stated in
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
24 April 2018
stated in
Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
24 April 2018
stated in
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
24 April 2018
stated in
Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
24 April 2018
stated in
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
24 April 2018
stated in
Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IGI
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P54279&geneProductId=UniProtKB:P54279
determination method
IEA
DNA mismatch repair
determination method
IBA
IEA
IGI
IMP
ISO
ISS
TAS
13 references
retrieved
14 February 2019
stated in
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P54279
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
ISO
retrieved
14 February 2019
stated in
Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
14 February 2019
stated in
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
14 February 2019
stated in
Different mutator phenotypes in Mlh1- versus Pms2-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
14 February 2019
stated in
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
14 February 2019
stated in
Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
14 February 2019
stated in
Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
14 February 2019
stated in
Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IMP
retrieved
14 February 2019
stated in
Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54279
determination method
IBA

Identifiers

 
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