Glutathione peroxidase 1 (Q21981126)

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mammalian protein found in Mus musculus
  • cellular glutathione peroxidase
  • selenium-dependent glutathione peroxidase 1
  • Gpx1
  • glutathione peroxidase 1
edit
Language Label Description Also known as
English
Glutathione peroxidase 1
mammalian protein found in Mus musculus
  • cellular glutathione peroxidase
  • selenium-dependent glutathione peroxidase 1
  • Gpx1
  • glutathione peroxidase 1

Statements

molecular function
glutathione peroxidase activity
determination method or standard
IDA
IEA
IMP
ISO
19 references
retrieved
1 January 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
ISO
retrieved
1 January 2018
stated in
Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Cellular glutathione peroxidase deficiency and endothelial dysfunction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
The effect of aging on glutathione peroxidase-i knockout mice-resistance of the lens to oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Effects of dietary iron overload on glutathione peroxidase knockout mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Mice with combined disruption of Gpx1 and Gpx2 genes have colitis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
The nature of antioxidant defense mechanisms: a lesson from transgenic studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P11352
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
1 January 2018
stated in
Developmental changes in murine brain antioxidant enzymes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IDA
retrieved
1 January 2018
stated in
Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IDA
glutathione peroxidase activity
determination method or standard
IBA
IDA
IEA
IMP
ISO
20 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
ISO
retrieved
14 February 2019
stated in
Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
The effect of aging on glutathione peroxidase-i knockout mice-resistance of the lens to oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
The nature of antioxidant defense mechanisms: a lesson from transgenic studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Effects of dietary iron overload on glutathione peroxidase knockout mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Cellular glutathione peroxidase deficiency and endothelial dysfunction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Mice with combined disruption of Gpx1 and Gpx2 genes have colitis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P11352
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
14 February 2019
stated in
Developmental changes in murine brain antioxidant enzymes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IDA
retrieved
14 February 2019
stated in
Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IBA
cell component
mitochondrion
determination method or standard
IDA
IEA
IMP
ISO
6 references
retrieved
31 January 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
ISO
retrieved
31 January 2018
stated in
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
31 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
31 January 2018
stated in
The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IDA
retrieved
31 January 2018
stated in
A mitochondrial protein compendium elucidates complex I disease biology
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IDA
retrieved
31 January 2018
stated in
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IDA
mitochondrion
determination method or standard
HDA
IDA
IEA
IMP
ISO
6 references
retrieved
1 January 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
ISO
retrieved
1 January 2018
stated in
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
1 January 2018
stated in
The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IDA
retrieved
1 January 2018
stated in
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
HDA
retrieved
1 January 2018
stated in
A mitochondrial protein compendium elucidates complex I disease biology
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
HDA
mitochondrion
determination method or standard
HDA
IBA
IDA
IEA
IMP
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
ISO
retrieved
14 February 2019
stated in
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
14 February 2019
stated in
The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IBA
retrieved
14 February 2019
stated in
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
HDA
retrieved
14 February 2019
stated in
A mitochondrial protein compendium elucidates complex I disease biology
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
HDA
biological process
response to reactive oxygen species
determination method or standard
IMP
5 references
retrieved
14 February 2019
stated in
Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Opposite roles of selenium-dependent glutathione peroxidase-1 in superoxide generator diquat- and peroxynitrite-induced apoptosis and signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Glutathione-peroxidase-1 null muscle progenitor cells are globally defective
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
response to oxidative stress
determination method or standard
IGI
IEA
IMP
9 references
retrieved
14 February 2019
stated in
Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Selenium-dependent cellular glutathione peroxidase protects mice against a pro-oxidant-induced oxidation of NADPH, NADH, lipids, and protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Glutathione-peroxidase-1 null muscle progenitor cells are globally defective
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Cellular glutathione peroxidase deficiency and endothelial dysfunction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IGI
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IEA
hydrogen peroxide catabolic process
determination method or standard
IEA
IMP
ISO
8 references
retrieved
1 January 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
ISO
retrieved
1 January 2018
stated in
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
The nature of antioxidant defense mechanisms: a lesson from transgenic studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11352&geneProductId=UniProtKB:P11352
determination method or standard
IEA
response to hydrogen peroxide
determination method or standard
IBA
IEA
IMP
ISO
ISS
6 references
retrieved
14 February 2019
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
ISO
retrieved
14 February 2019
stated in
Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IBA
hydrogen peroxide catabolic process
determination method or standard
IBA
IEA
IMP
ISO
9 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
ISO
retrieved
14 February 2019
stated in
Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
The nature of antioxidant defense mechanisms: a lesson from transgenic studies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
Targeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11352
determination method or standard
IBA

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21981126&oldid=2174117565"