Nuclear transcription factor-Y alpha (Q21985879)

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mammalian protein found in Mus musculus

nuclear transcription factor Y subunit alpha
nuclear transcription factor Y subunit A
NF-YA
Nfya
CAAT box DNA-binding protein subunit A

Language	Label	Description	Also known as
English	Nuclear transcription factor-Y alpha	mammalian protein found in Mus musculus	nuclear transcription factor Y subunit alpha nuclear transcription factor Y subunit A NF-YA Nfya CAAT box DNA-binding protein subunit A

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Nuclear transcription factor Y subunit A

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23708

CCAAT-binding factor, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

DNA-binding transcription factor activity

determination method

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

determination method

6 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method

4 references

5 June 2018

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23708&geneProductId=UniProtKB:P23708

determination method

5 June 2018

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23708&geneProductId=UniProtKB:P23708

determination method

14 February 2019

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

core promoter sequence-specific DNA binding

determination method

1 reference

24 April 2018

Transcription factor NF-Y is a functional regulator of the transcription of core clock gene Bmal1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23708&geneProductId=UniProtKB:P23708

determination method

protein binding

determination method

3 references

14 February 2019

Interaction between the two ubiquitously expressed transcription factors NF-Y and Sp1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Interaction between the two ubiquitously expressed transcription factors NF-Y and Sp1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

sequence-specific DNA binding

determination method

1 reference

14 February 2019

Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

transcription coregulator binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

transcription factor binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

CCAAT-binding factor complex

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

protein-DNA complex

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

determination method

5 references

14 February 2019

Subunits of the heterotrimeric transcription factor NF-Y are imported into the nucleus by distinct pathways involving importin beta and importin 13.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

The short isoform of NF-YA belongs to the embryonic stem cell transcription factor circuitry

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

determination method

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

RNA polymerase II transcription regulator complex

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

biological process

positive regulation of transcription, DNA-templated

determination method

3 references

14 February 2019

Transcription factor NF-Y is a functional regulator of the transcription of core clock gene Bmal1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta gene

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

regulation of stem cell population maintenance

determination method

1 reference

5 June 2018

The short isoform of NF-YA belongs to the embryonic stem cell transcription factor circuitry

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23708&geneProductId=UniProtKB:P23708

determination method

positive regulation of stem cell proliferation

determination method

1 reference

5 June 2018

The short isoform of NF-YA belongs to the embryonic stem cell transcription factor circuitry

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23708&geneProductId=UniProtKB:P23708

determination method

transcription, DNA-templated

determination method

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23708&geneProductId=UniProtKB:P23708

determination method

positive regulation of transcription by RNA polymerase II

determination method

3 references

14 February 2019

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

14 February 2019

Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

rhythmic process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23708

determination method

transcription by RNA polymerase II

determination method

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23708&geneProductId=UniProtKB:P23708

determination method

CCAAT-binding factor, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23708

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000077853

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000077853

ENSMUSP00000123785

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000123785

ENSMUSP00000043909

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000043909

ENSMUSP00000124115

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000124115

ENSMUSP00000124245

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000124245

ENSMUSP00000124404

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000124404

ENSMUSP00000124501

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000124501

ENSMUSP00000124965

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000124965

ENSMUSP00000125034

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000125034

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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