Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity (Q28186572)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12659851%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12659851%20AND%20SRC:MED&resulttype=core&format=json

Nuclear transcription factor-Y alpha

1 November 2019

main subject

1 reference

GOA release 2020-03-11

author

Frank S. Lee

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12659851%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

Jianhe Huang

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12659851%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Zheng Tu

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12659851%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

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publication date

1 April 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12659851%20AND%20SRC:MED&resulttype=core&format=json

Biochemical and Biophysical Research Communications

1 November 2019

number of pages

9

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based on heuristic

inferred from page(s)

published in

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1 November 2019

volume

303

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1 November 2019

issue

2

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1 November 2019

page(s)

532-540

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Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 November 2019

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Signal transduction by the JNK group of MAP kinases

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MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

7 January 2021

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

7 January 2021

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Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

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Missing pieces in the NF-kappaB puzzle

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Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

7 January 2021

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Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

7 January 2021

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Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

7 January 2021

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JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

7 January 2021

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Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation

7 January 2021

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MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway

7 January 2021

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MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells

7 January 2021

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Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction

7 January 2021

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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

7 January 2021

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MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

7 January 2021

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MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

7 January 2021

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The essential role of MEKK3 in TNF-induced NF-kappaB activation

7 January 2021

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MAP kinase pathways in yeast: for mating and more

7 January 2021

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Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae

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A mammalian scaffold complex that selectively mediates MAP kinase activation

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MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

7 January 2021

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JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

7 January 2021

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Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

7 January 2021

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A subdomain of MEKK1 that is critical for binding to MKK4

7 January 2021

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MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression

7 January 2021

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

7 January 2021

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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

7 January 2021

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Role of the amino-terminal domains of MEKKs in the activation of NF kappa B and MAPK pathways and in the regulation of cell proliferation and apoptosis.

7 January 2021

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Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

7 January 2021

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The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-291X(03)00387-5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12659851%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference