Intraflagellar transport 172 (Q21986467)

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mammalian protein found in Mus musculus

intraflagellar transport 172 protein
selective LIM-binding factor Wimple
Ift172
intraflagellar transport protein 172 homolog
intraflagellar transport 172 homolog
protein wimple

Language	Label	Description	Also known as
English	Intraflagellar transport 172	mammalian protein found in Mus musculus	intraflagellar transport 172 protein selective LIM-binding factor Wimple Ift172 intraflagellar transport protein 172 homolog intraflagellar transport 172 homolog protein wimple

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Tetratricopeptide-like helical domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6VH22

WD40/YVTN repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6VH22

WD40-repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6VH22

Armadillo-type fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6VH22

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

3 references

9 May 2019

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

transcription factor binding

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

intraciliary transport particle B

determination method

3 references

24 April 2018

The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6VH22&geneProductId=UniProtKB:Q6VH22

determination method

24 April 2018

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6VH22&geneProductId=UniProtKB:Q6VH22

determination method

24 April 2018

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6VH22&geneProductId=UniProtKB:Q6VH22

determination method

cell projection

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

sperm principal piece

determination method

1 reference

9 May 2019

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

determination method

1 reference

9 May 2019

Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

sperm cytoplasmic droplet

determination method

1 reference

9 May 2019

CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

determination method

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

intraciliary transport particle B

determination method

4 references

9 May 2019

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

biological process

Notch signaling pathway

determination method

1 reference

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

roof of mouth development

determination method

1 reference

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

positive regulation of smoothened signaling pathway

determination method

1 reference

9 May 2019

Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

protein processing

determination method

1 reference

9 May 2019

Cilia and Hedgehog responsiveness in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

limb development

determination method

3 references

9 May 2019

Generation of mice with a conditional allele for Ift172

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

multicellular organism development

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

determination method

1 reference

9 May 2019

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

regulation of smoothened signaling pathway

determination method

1 reference

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

heart development

determination method

1 reference

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

neural tube closure

determination method

1 reference

9 May 2019

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

determination of left/right symmetry

determination method

1 reference

9 May 2019

Analysis of mouse embryonic patterning and morphogenesis by forward genetics

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

brain development

determination method

1 reference

9 May 2019

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

hindgut development

determination method

1 reference

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

neural tube development

determination method

1 reference

9 May 2019

Generation of mice with a conditional allele for Ift172

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

cytoplasmic microtubule organization

determination method

1 reference

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

epidermis development

determination method

1 reference

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

negative regulation of epithelial cell proliferation

determination method

1 reference

9 May 2019

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

smoothened signaling pathway

determination method

1 reference

9 May 2019

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

spinal cord motor neuron differentiation

determination method

1 reference

9 May 2019

Complex interactions between genes controlling trafficking in primary cilia

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

bone development

determination method

1 reference

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

dorsal/ventral pattern formation

determination method

4 references

9 May 2019

Complex interactions between genes controlling trafficking in primary cilia

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Hedgehog signalling in the mouse requires intraflagellar transport proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Analysis of mouse embryonic patterning and morphogenesis by forward genetics

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Cilia and Hedgehog responsiveness in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

neural tube formation

determination method

1 reference

9 May 2019

Hedgehog signalling in the mouse requires intraflagellar transport proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

cilium assembly

determination method

6 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Hedgehog signalling in the mouse requires intraflagellar transport proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Complex interactions between genes controlling trafficking in primary cilia

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

intraciliary transport

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VH22

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6VH22

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000049335

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000049335

ENSMUSP00000143995

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143995

ENSMUSP00000144216

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144216

ENSMUSP00000144425

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144425

Sitelinks

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Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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