Complex interactions between genes controlling trafficking in primary cilia (Q28512423)

25 January 2017

title

Complex interactions between genes controlling trafficking in primary cilia (English)

1 reference

Dynein cytoplasmic 2 heavy chain 1

25 January 2017

main subject

1 reference

Intraflagellar transport 172

1 reference

Patched 1

1 reference

Intraflagellar transport 122

1 reference

Sonic hedgehog

1 reference

GLI-Kruppel family member GLI2

1 reference

GLI-Kruppel family member GLI3

1 reference

1 reference

4

Kathryn V. Anderson

1 reference

25 January 2017

author name string

Polloneal Jymmiel R. Ocbina

series ordinal

1

1 reference

25 January 2017

Jonathan T. Eggenschwiler

series ordinal

2

1 reference

25 January 2017

Ivan Moskowitz

series ordinal

3

1 reference

25 January 2017

language of work or name

English

0 references

publication date

1 June 2011

1 reference

25 January 2017

1 reference

25 January 2017

volume

43

1 reference

25 January 2017

issue

6

1 reference

25 January 2017

page(s)

547–553

1 reference

describes a project that uses

25 January 2017

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3132150/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Cranioectodermal Dysplasia, Sensenbrenner syndrome, is a ciliopathy caused by mutations in the IFT122 gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Retrograde intraflagellar transport mutants identify complex A proteins with multiple genetic interactions in Chlamydomonas reinhardtii

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

19 March 2017

1 reference

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Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling

19 March 2017

1 reference

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DYNC2H1 mutations cause asphyxiating thoracic dystrophy and short rib-polydactyly syndrome, type III

19 March 2017

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A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies

19 March 2017

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Ciliary abnormalities due to defects in the retrograde transport protein DYNC2H1 in short-rib polydactyly syndrome

19 March 2017

1 reference

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Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling.

19 March 2017

1 reference

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Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4

19 March 2017

1 reference

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FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism

19 March 2017

1 reference

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Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts

19 March 2017

1 reference

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THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

19 March 2017

1 reference

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Dissection of epistasis in oligogenic Bardet-Biedl syndrome

19 March 2017

1 reference

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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Vertebrate Smoothened functions at the primary cilium

19 March 2017

1 reference

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Cilia and Hedgehog responsiveness in the mouse

19 March 2017

1 reference

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Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

19 March 2017

1 reference

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Hedgehog signalling in the mouse requires intraflagellar transport proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

A novel dynein light intermediate chain colocalizes with the retrograde motor for intraflagellar transport at sites of axoneme assembly in chlamydomonas and Mammalian cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

19 March 2017

https://api.crossref.org/works/10.1038%2FNG.832

Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Protein particles in Chlamydomonas flagella undergo a transport cycle consisting of four phases

19 March 2017

1 reference

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Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

19 March 2017

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Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas

19 March 2017

1 reference

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Distinct mutants of retrograde intraflagellar transport (IFT) share similar morphological and molecular defects

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Altered neural cell fates and medulloblastoma in mouse patched mutants

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

The primary cilium: a signalling centre during vertebrate development

19 March 2017

1 reference

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Patched1 regulates hedgehog signaling at the primary cilium

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

The ciliary proteome database: an integrated community resource for the genetic and functional dissection of cilia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Genome-wide identification of mouse congenital heart disease loci

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Functional modules, mutational load and human genetic disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Making sense of cilia in disease: the human ciliopathies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Piecing together a ciliome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3132150

Evidence of Oligogenic Inheritance in Nephronophthisis

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.832

Intraflagellar transport is essential for endochondral bone formation.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.832

Jeune asphyxiating thoracic dystrophy and short-rib polydactyly type III (Verma-Naumoff) are variants of the same disorder

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21552265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.832

1 reference

1 reference

1 reference

1 reference