Protein tyrosine phosphatase, receptor type, N polypeptide 2 (Q21990493)

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mammalian protein found in Mus musculus

protein tyrosine phosphatase-NP
IA-2 beta
R-PTP-N2
PTP-NP
receptor-type tyrosine-protein phosphatase N2
Ptprn2
PTP IA-2beta

Language	Label	Description	Also known as
English	Protein tyrosine phosphatase, receptor type, N polypeptide 2	mammalian protein found in Mus musculus	protein tyrosine phosphatase-NP IA-2 beta R-PTP-N2 PTP-NP receptor-type tyrosine-protein phosphatase N2 Ptprn2 PTP IA-2beta

Statements

1 reference

25 May 2022

UniProt protein ID

Receptor-type tyrosine-protein phosphatase-like N/N2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

Protein-tyrosine phosphatase-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

Protein-tyrosine phosphatase receptor IA-2, ectodomain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Tyrosine specific protein phosphatases domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PTP type protein phosphatase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

RESP18 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase receptor IA-2 ectodomain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

phosphoprotein phosphatase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

phosphatase activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

hydrolase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

protein binding

determination method

1 reference

9 May 2019

Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

integral component of membrane

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

secretory granule membrane

determination method

1 reference

9 May 2019

Disturbances in the secretion of neurotransmitters in IA-2/IA-2beta null mice: changes in behavior, learning and lifespan

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

transport vesicle membrane

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

cytoplasmic vesicle

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

secretory granule

determination method

4 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

9 May 2019

Myosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

integral component of synaptic vesicle membrane

determination method

1 reference

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P80560&geneProductId=UniProtKB:P80560

determination method

biological process

protein dephosphorylation

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

peptidyl-tyrosine dephosphorylation

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

dephosphorylation

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

insulin secretion involved in cellular response to glucose stimulus

determination method

1 reference

14 February 2019

Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

neurotransmitter secretion

determination method

1 reference

9 May 2019

Disturbances in the secretion of neurotransmitters in IA-2/IA-2beta null mice: changes in behavior, learning and lifespan

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

lipid metabolism

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80560

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

Protein-tyrosine phosphatase, catalytic

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

Protein-tyrosine phosphatase receptor IA-2 ectodomain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

PTP type protein phosphatase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

Tyrosine specific protein phosphatases domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

Protein-tyrosine phosphatase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P80560

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000139978

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000139978

ENSMUSP00000064046

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000064046

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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